Results 91 to 100 of about 901,213 (331)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Аnalysis of the causes and methods used to mitigate scale deposits at the production wells in Western Siberia

open access: yesНаука. Инновации. Технологии
A comprehensive analysis of all failures and replacements of subsurface lifting equipment in one region of Western Siberia on a well stock with problems due to scale deposits has been carried out.
D. A. Ivanov   +4 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

РОЗРАХУНОК ПОКАЗНИКІВ НАДІЙНОСТІ ПОСЛІДОВНО З’ЄДНАНИХ І РЕЗЕРВОВАНИХ ЕЛЕМЕНТІВ БЕЗ ВІДНОВЛЕННЯ ДЛЯ ДИФУЗІЙНО-НЕМОНОТОННОГО РОЗПОДІЛУ ЇХ ВІДМОВ

open access: yesSučasnì Informacìjnì Tehnologìï u Sferì Bezpeki ta Oboroni, 2015
В роботі здійснено розрахунок ймовірності безвідмовної роботи послідовно з’єднаних і резервованих елементів без відновлення для дифузійно–немонотонного (ДН) розподілу їх відмов. Розрахунки здійснені для виробів електронного типу.
Volodymyr I. Mirnenko   +2 more
doaj  

A Statistical State Analysis of a Marine Gas Turbine

open access: yesActuators, 2019
This paper describes the analysis, from a statistical point of view, of a maritime gas turbine, under various operating conditions, so as to determine its state.
Suzana Lampreia   +3 more
doaj   +1 more source

Instant restore after a media failure

open access: yes, 2017
Media failures usually leave database systems unavailable for several hours until recovery is complete, especially in applications with large devices and high transaction volume.
C Mohan   +8 more
core   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Markov Model-Based Reliability Analysis Considering the Redundancy Effect of Modular Converters

open access: yesIEEE Access
This paper uses a DAB converter and a non-isolated DC-DC converter as modules. It analyzes the differences in circuit characteristics and reliability due to the redundancy effect by combining them in series and parallel.
Jae-Seong Jo   +5 more
doaj   +1 more source

Pre-Dispatch of Load in Thermoelectric Power Plants Considering Maintenance Management Using Fuzzy Logic

open access: yesIEEE Access, 2018
This paper presents a new method for load pre-dispatch considering the technical conditions of engines in thermoelectric power plants by combining several maintenance and diagnostic techniques and using computational intelligence.
Milton Fonseca   +4 more
doaj   +1 more source

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