ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann +6 more
wiley +1 more source
Shear Bond Strength Between Artificial Teeth and Denture Base Resins Fabricated by Conventional, Milled, and 3D-Printed Workflows: An In Vitro Study. [PDF]
Verniani G +4 more
europepmc +1 more source
On designing dependable services with diverse off-the-shelf SQL servers [PDF]
A. Avizienis +25 more
core +1 more source
Quantitative Assessment of Upper Limb Ataxia Using a Virtual Reality‐Based Evaluation System
ABSTRACT Objective Cerebellar ataxia impairs coordination and balance, reducing quality of life. Conventional clinical scales, including the Scale for the Assessment and Rating of Ataxia (SARA) and the International Cooperative Ataxia Rating Scale (ICARS), are widely used to assess ataxia but are limited by subjectivity and inter‐rater variability ...
Masayuki Sato +5 more
wiley +1 more source
Analysis of Risk Factors Related to Early Implant Failures in Patients Attending a Private Practice Setting: A Retrospective Study. [PDF]
Guarnieri R +5 more
europepmc +1 more source
Diffusion Tractography Biomarker for Epilepsy Severity in Children With Drug‐Resistant Epilepsy
ABSTRACT Objective To develop a novel deep‐learning model of clinical DWI tractography that can accurately predict the general assessment of epilepsy severity (GASE) in pediatric drug‐resistant epilepsy (DRE) and test if it can screen diverse neurocognitive impairments identified through neuropsychological assessments.
Jeong‐Won Jeong +7 more
wiley +1 more source
The clinical outcomes of joint-preserving endoprosthesis reconstruction for primary sarcomas about the knee. [PDF]
Li Z, Liu W, Niu X, Jiang C, Zhang Q.
europepmc +1 more source
ABSTRACT Background Mitofusin 2 (MFN2) is a major causative gene for axonal Charcot – Marie – Tooth disease type 2A (CMT2A), with a wide phenotypic spectrum. Comprehensive large ‐ scale genotype – phenotype association studies are essential for understanding disease pathogenesis and improved clinical management.
Masahiro Ando +13 more
wiley +1 more source
A comparative analysis of adhesion abilities between AH Plus<sup>®</sup> Bioceramic, Ceraseal<sup>®</sup> and AH Plus<sup>®</sup> on root canal dentine surfaces. [PDF]
Maharti ID +5 more
europepmc +1 more source

