Results 61 to 70 of about 3,844,361 (299)

Comparison of reliability techniques of parametric and non-parametric method

open access: yesEngineering Science and Technology, an International Journal, 2016
Reliability of a product or system is the probability that the product performs adequately its intended function for the stated period of time under stated operating conditions. It is function of time.
C. Kalaiselvan, L. Bhaskara Rao
doaj   +1 more source

m-Consecutive-k-out-of-n: F Structures with a Single Change Point

open access: yesMathematics, 2020
In the present article, we introduce the m-consecutive-k-out-of-n:F structures with a single change point. The aforementioned system consists of n independent components, of which the first n1 units are identically distributed with common reliability p1,
Ioannis S. Triantafyllou
doaj   +1 more source

Maximum Likelihood Performance of Mean Time to Failure for Right-Censored Data [PDF]

open access: yes, 2009
In this paper failure times following Weibull, exponential and log-normal distribution are considered. The parameters of these distributions are estimated by the maximum likelihood method and these values are used to estimate other quantity of ...
Ibrahim, Noor Akma, Ng, Poh Bee
core  

Creep failure in a threshold activated dynamics: Role of temperature during a sub-critical loading [PDF]

open access: yes, 2019
Creep is a time-dependent deformation of solids at relatively low stresses, leading to the breakdown with time. Here we propose a simple model for creep failure of disordered solids, in which temperature and stress are controllable.
Hatano, Takahiro, Roy, Subhadeep
core   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Stochastic Analysis of a Priority Standby System under Preventive Maintenance

open access: yesApplied Sciences, 2021
In this paper, we propose a system of two dissimilar units: one unit prioritizes operation (priority unit), and the other unit is kept as a cold standby (ordinary unit). In this system, we assume that the failures, repairs, and preventive maintenance (PM)
Khalaf S. Sultan, Mohamed E. Moshref
doaj   +1 more source

Advancing Dynamic Fault Tree Analysis

open access: yes, 2016
This paper presents a new state space generation approach for dynamic fault trees (DFTs) together with a technique to synthesise failures rates in DFTs. Our state space generation technique aggressively exploits the DFT structure --- detecting symmetries,
Junges, Sebastian   +2 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Stochastic Analysis to Calculate the Mean Time to System Failure (MTSF) of A Two Identical Unit Parallel System

open access: yesZanco Journal of Humanity Sciences
In this research two identical parallel electric generators with repair a failed one have been analyzed stochastically by two methods, first by method based on certain probability assumptions and second through three state Markov chain, classified as ...
Bestun Merza Abdulkareem
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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