Results 81 to 90 of about 1,446,763 (330)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Understanding the shape of the mixture failure rate (with engineering and demographic applications) [PDF]
Mixtures of distributions are usually effectively used for modeling heterogeneity. It is well known that mixtures of DFR distributions are always DFR. On the other hand, mixtures of IFR distributions can decrease, at least in some intervals of time.
Maxim S. Finkelstein
core
Spektrum Industri: Jurnal Ilmiah Pengetahuan dan Penerapan Teknik IndustriThe textile industry, particularly sock manufacturing, faces increasing demands for productivity and cost efficiency amid global competition. This study presents a comprehensive case study on optimizing sock production in a South African knitting plant ...
Kemlall Ramdass, Isaac Olalere
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Failure time data modeling and analysis
, 2012 textThis report presents the descriptive data analysis and failure time modeling that can be used to find out the characteristics and pattern of failure time.
Zhu, Chen, master of science in engineering
core
Defender: A Low Overhead and Efficient Fault-Tolerant Mechanism for Reliable on-Chip Router
IEEE Access, 2019 The ever-shrinking size of a transistor has made Network on Chip (NoC) susceptible to faults. A single error in the NoC can disrupt the entire communication.
Naveed Khan Baloch +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Reliability analysis of two-unit cold standby repairable systems under Poisson shock. [PDF]
, 2011 This paper analyses the reliability of a cold standby system consisting of two re- pairable units, a switch and a repairman. At any time, one of the two units is operating while the other is on cold standby.
Shaomin Wu +3 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source