Results 81 to 90 of about 3,844,361 (299)

Scale Invariance in the Nonstationarity of Physiological Signals [PDF]

, 2000
We introduce a segmentation algorithm to probe temporal organization of heterogeneities in human heartbeat interval time series. We find that the lengths of segments with different local values of heart rates follow a power-law distribution.
A. Arneodo, A. L. Goldberger, A. Witt, C. Guilleminault, C.-K. Peng, G. Mayer-Kress, H. A. Makse, H. Eugene Stanley, H. Kantz, J. B. Bassingthwaighte, J. M. Hausdorff, L. S. Liebovitch, Luís A. Nunes Amaral, M. Kobayashi, M. M. Wolf, M. Meyer, P. Ch. Ivanov, P. Ch. Ivanov, Pedro Bernaola-Galván, Plamen Ch. Ivanov, R. Hegger, R. I. Kitney, R. L. Stratonovich, T. Schreiber, W. H. Press   +24 more
core   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

A Probabilistic Approach for Threshold Reliability Structures with Three Different Types of Components

Mathematics
In the present work, we study threshold reliability systems consisting of three different kinds of independent components. Within these structures, the components belonging to the same type, share a common reliability and the same weight. The reliability
Ioannis S. Triantafyllou
doaj   +1 more source

Neutrosophic Reliability Assessment of Hydroelectric Power Plant using Universal Generating Function Technique [PDF]

Neutrosophic Sets and Systems
The main objective of present study is to assess the reliability measures of a hydroelectric power plant under neutrosophic environment. There are several reliability evaluations like Markovian approach, Semi-Markovian approach, etc.
Kanak Saini, Monika Saini, Ashish Kumar , Dinesh Kumar Saini   +3 more
doaj   +1 more source

Er:YAG laser, piezosurgery, and surgical drill for bone decortication during orthodontic mini-implant insertion: primary stability analysis-an animal study [PDF]

, 2017
It is important to identify factors that affect primary stability of orthodontic mini-implants because it determines the success of treatment. We assessed mini-implant primary stability (initial mechanical engagement with the bone) placed in pig jaws. We
Matys, Jacek, Flieger, RafaÅ‚, Tenore, Gianluca, Grzech-LeÅ›niak, Kinga, Romeo, Umberto, Dominiak, Marzena   +5 more
core   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Optimization of Socks Production in South African Knitting Plant: A Cost-Effective Alternative to Industry 4.0

Spektrum Industri: Jurnal Ilmiah Pengetahuan dan Penerapan Teknik Industri
The textile industry, particularly sock manufacturing, faces increasing demands for productivity and cost efficiency amid global competition. This study presents a comprehensive case study on optimizing sock production in a South African knitting plant ...
Kemlall Ramdass, Isaac Olalere
doaj   +1 more source

On Dependability in Distributed Databases [PDF]

, 1992
Distributed database availability, reliability, and mean transaction completion time are derived for repairable database systems in which each component is continuously available for repair.
Teorey, Toby J.
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source