Results 71 to 80 of about 1,446,763 (330)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
, 2011 The official published version can be found at the link below.In this paper, the reliable H∞ filtering problem is investigated for a class of uncertain discrete time-delay systems with randomly occurred nonlinearities (RONs) and sensor failures. RONs are
Liu, Y +5 more
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
On the Limits of Greenwich Mean Time, or The Failure of a Modernist Revolution
, 2014 On the Limits of Greenwich Mean Time, or The Failure of a Modernist Revolution From the introduction of World Standard Time in 1884 to Einstein’s theory of relativity, the nature and regulation of time was a highly contested issue in modernism, with ...
Huber, Irmtraud
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Mean time to failure for periodic failure rate
, 2009 The paper is concerned with the determination of the Mean Time To Failure (MTTF) in configurations where the failure rate is periodical. After solving two configurations exactly, we show that when the period of the failure rate oscillations is small with
Tanguy, C.
core
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
MathematicsIn the present work, we study threshold reliability systems consisting of three different kinds of independent components. Within these structures, the components belonging to the same type, share a common reliability and the same weight. The reliability
Ioannis S. Triantafyllou
doaj +1 more source
Neutrosophic Reliability Assessment of Hydroelectric Power Plant using Universal Generating Function Technique [PDF]
Neutrosophic Sets and SystemsThe main objective of present study is to assess the reliability measures of a hydroelectric power plant under neutrosophic environment. There are several reliability evaluations like Markovian approach, Semi-Markovian approach, etc.
Kanak Saini +3 more
doaj +1 more source