Results 101 to 110 of about 89,725,173 (290)
Understanding the shape of the mixture failure rate (with engineering and demographic applications) [PDF]
Mixtures of distributions are usually effectively used for modeling heterogeneity. It is well known that mixtures of DFR distributions are always DFR. On the other hand, mixtures of IFR distributions can decrease, at least in some intervals of time.
Maxim S. Finkelstein
core
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Review of fault detection, localization and tolerant in multilevel inverter
Energy ReportsMultilevel inverters (MLIs) find a wide range of applications in high and medium-power applications, including electric vehicles, FACTS devices, HVDC, and renewable energy systems. Since it utilizes a large number of semiconductor devices and capacitors,
Hillol Phukan +3 more
doaj +1 more source
Testing for change in mean of heteroskedastic time series [PDF]
In this paper we consider a Lagrange Multiplier-type test (LM) to detect change in the mean of time series with heteroskedasticity of unknown form. We derive the limiting distribution under the null, and prove the consistency of the test against the ...
Mohamed Boutahar
core
The Effect of Door-to-Diuretic Time on Clinical Outcomes in Patients With Acute Heart Failure
, 2018 OBJECTIVES: This study sought to examine the impact of door-to-diuretic (D2D) time on mortality in patients with acute heart failure (AHF) who were presenting to an emergency department (ED).
오재원, 강석민
core +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
MathematicsThis paper studies the reliability and availability of a k-out-of-(M+S) retrial machine repair system with two-way communication, consisting of M primary components and S warm standby components.
Chen-Hsiang Hsieh +3 more
doaj +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Cost Analysis of Two-Unit Cold Standby Repairable Redundant System Involving Common Cause Failures and Preventive Maintenance [PDF]
The Egyptian Statistical Journal, 2013 M.Y. Haggag +2 more
doaj +1 more source