Results 101 to 110 of about 1,446,763 (330)

A single-phase seven-level switched capacitor with common ground inverter and improved phase-shift modulation technique

open access: yesScientific Reports
Lately, transformer-less Researchers in the fields of power electronics and renewable energy have taken notice of photovoltaic inverters because of their great efficiency, low cost, and small size.
Bisma Saif   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Modeling failure of high performance fibers: on the prediction of long-term time-to-failure

open access: yes, 2015
Our objective is to predict the time-to-failure distribution of fibers at loads for which mean time-to-failure is comparable or longer than the fibers’ economic lifetime.
Hulshof, J   +2 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

KARAKTERISTIK UMUR PRODUK PADA MODEL WEIBULL

open access: yesMedia Statistika, 2009
Long life of product can reflect its quality. Generally, good products have long life. There are functions that relationship with life as reliability function, hazard rate function, mean time to failure, and mean residual life.
Sudarno Sudarno
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Stochastically ordered subpopulations and optimal burn-in procedure [PDF]

open access: yes
Burn-in is a widely used engineering method which is adopted to eliminate defective items before they are shipped to customers or put into the field operation.
Maxim S. Finkelstein, Ji Cha
core  

Systematic Routine for Setting Confidence Levels for Mean Time to Failure (MTTF) [PDF]

open access: yes, 2014
There are circumstances where an item is intentionally tested to destruction.  The purpose of this technique is to determine the failure rate (λ) of a tested item.
Parsons, Donna   +2 more
core  

Reliability and Availability Analysis of k-out-of-M+S Retrial Machine Repair System with Two-Way Communication

open access: yesMathematics
This paper studies the reliability and availability of a k-out-of-(M+S) retrial machine repair system with two-way communication, consisting of M primary components and S warm standby components.
Chen-Hsiang Hsieh   +3 more
doaj   +1 more source

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