Results 101 to 110 of about 3,844,361 (299)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Scientific ReportsLately, transformer-less Researchers in the fields of power electronics and renewable energy have taken notice of photovoltaic inverters because of their great efficiency, low cost, and small size.
Bisma Saif +4 more
doaj +1 more source
A Bayesian analysis of the PPP puzzle using an unobserved components model [PDF]
The failure to describe the time series behaviour of most real exchange rates as temporary deviations from fixed long-term means may be due to time variation of the equilibria themselves, see Engel (2000).
Dijk, H.K. van, Kleijn, R.H.
core +1 more source
Nucleon-Nucleon Scattering under Spin-Isospin Reversal in Large-N_c QCD
, 2003 The spin-flavor structure of certain nucleon-nucleon scattering observables derived from the large N_c limit of QCD in the kinematical regime where time-dependent mean-field theory is valid is discussed.
A.V. Belitsky +21 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Forecasting reliability of ShADR-32M coolant flow rate sensors
Nuclear Energy and Technology, 2017 Complexity of technical systems, such as NPPs, implicates the necessity to undertake efforts for assessment of reliability of equipment, especially critical equipment influencing the reactor operation safety.
A.I. Pereguda, V.I. Belozerov
doaj +1 more source
Variance reduction in mean time to failure simulations [PDF]
Proceedings of the 20th conference on Winter simulation - WSC '88, 1988 P. Shababuddin +4 more
openaire +1 more source
Availability and mean time between failures of redundant systems with random maintenance of subsystems [PDF]
It is shown how the availability and MTBF (Mean Time Between Failures) of a redundant system with subsystems maintenanced at the points of so-called stationary renewal processes can be determined from the distributions of the intervals between ...
Schneeweiss, W.
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source