Results 221 to 230 of about 6,190,775 (296)

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

Doing Science With Our Grandmother's WISDOM: A Worldview Integrating Sociality, Diversity, and Observant Meaning-Making. [PDF]

Am J Hum Biol
Dajani R, Glass D, Fuentes A.
europepmc   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Acknowledging existential moments and meaning-making in palliative care: A hermeneutic study of physicians' experience. [PDF]

Palliat Support Care
Kelly MA, McLeod E.
europepmc   +1 more source

Making Meaning Making

, 2016
Hasager, Maj,, Lund University.
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Drawing cancer chronicles: A qualitative study to evaluate narrative meaning-making over time and in response to a meaning-centred care intervention. [PDF]

PLoS One
Evans ERE, van Poecke N, Portela M, Scherer-Rath M, Weeseman Y, Bood ZM, Christophe N, Dörr H, de Vos-Geelen J, Beeker A, de Klerk G, Bras E, Vlug H, Bossink F, Savelkoul F, Timmermans LM, Sprangers MAG, Helmich E, van Laarhoven HWM.   +18 more
europepmc   +1 more source

Understanding lightbulb moments: Meaning-making in visual morphology from comics and emoji. [PDF]

Mem Cognit
Lichtenberg LD, Klomberg B, Schilperoord J, Cohn N.   +3 more
europepmc   +1 more source

Iterative Situated Engagement Perspective: Meaning-Making Challenges Across Cancer Screening Phases. [PDF]

Cancers (Basel)
Lemmo D, Martino ML, Bianco R, Donizzetti AR, Freda MF, Caso D.   +5 more
europepmc   +1 more source

Coping and Meaning-Making Strategies Described by Parents of Children with Medical Complexity. [PDF]

Clin Pract Pediatr Psychol
Tager JB, Kenney AE, Lim PS, Everhart SA, Johaningsmeir S, Balistreri KA, Morgan-Tautges A, Lee KJ, Brophey MA, Scanlon MC, Rothschild CB, Davies WH, Schnell JL.   +12 more
europepmc   +1 more source