Results 111 to 120 of about 243,984 (315)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Explaining the model of mental health based on the style of attachment to God intensity on the of stressful events with the mediation of religious beliefs and meaning and purpose in life in women victims of marital infidelity [PDF]

open access: yesمجله علوم روانشناختی
Background: Marital infidelity, as a significant stressful life event, can profoundly impact individuals' mental health. Religious beliefs and meaning in life, as psychological resources, play a crucial role in mitigating the adverse effects of stressors.
Maryam Mahdavi   +3 more
doaj  

The Role of Existential Psychological Challenges in Chinese Adolescents’ School Aversion and Dropout and School Refusal Behavior

open access: yesAdvances in Education, Humanities and Social Science Research
In order to explore how existential psychological crises impact school rejection and dropout rates among Chinese teenagers, a mixed-methods approach is employed.
Zimu Zhu   +3 more
semanticscholar   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

What is life worth living for? A systematic review on meaning in life and meaning in work as protective factors for healthcare professionals’ wellbeing

open access: yes
The wellbeing of healthcare professionals is a topic of utmost importance in public health, given the close connection be-tween healthcare professionals’ mental health and their ability to provide high-quality care. A promising protective resource is the
Gaia Corbella   +2 more
core   +1 more source

What is the relationship between Meaning in Life, Purpose in Life and secondary student wellbeing?

open access: yes, 2015
This study followed one male secondary school cohort over three years, prior and during a positive education implementation at their school. The purpose of this research was two-fold.
Rachel Riedel (20240805)
core   +1 more source

Development and structure of the meaning of life dimensional scale. [PDF]

open access: yes, 2011
En los últimos años ha aumentado considerablemente el interés por identificar factores específicos que pueden influir en nuestra salud, principalmente aspectos como el sentido de vida, la felicidad y la búsqueda de metas.
Martínez-Ortiz, Efrén   +3 more
core   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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