Results 61 to 70 of about 166,958,153 (304)
Social SciencesThe inclusion of refugees in the formal labor markets of host countries has been recognized as a sustainable solution to forced migration. In Brazil, due to the growing number of refugees, it is urgent to look at the difficulties faced by this population
Renata Avancini Tonini +6 more
doaj +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Psicologia em Estudo, 2008 Seguem aqui alguns dos resultados de uma pesquisa cujo objetivo foi investigar os sentidos do trabalho para sujeitos inseridos em um "empreendimento solidário", a partir do estudo de caso de uma cooperativa de serviços gerais.
Márcia Luíza Pit Dal Magro +1 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The meaning and experience of work in the context of severe and enduring mental health problems: An interpretative phenomenological analysis [PDF]
, 2013 This is the author's final version of the article. The final publication is available from the link below. Copyright @ 2013 IOS Press and the Authors.Research into mental health and employment has indicated that work holds multiple meanings for people ...
Reynolds, F. +7 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
There's no business like sportbusiness [PDF]
, 2005 Oratie bij de aanvaarding van het lectoraat Sportbusiness aan de Fontys Economische Hogeschool Tilburg op 8 juni ...
Bottenburg,van, Maarten +4 more
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