Results 101 to 110 of about 14,437 (302)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Norms and compactness of operators on absolute weighted mean summable series
In a recent paper [16], we characterized the classes of triangular matrix transformations mapping the spaces INpI and INqIk into the spaces INqIk and INqI, respectively, where the space INpIk, of series summable by absolute summability method.
Mehmet A. Sarigol
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Generic measures for hyperbolic flows on non-compact spaces [PDF]
Yves Coudène, Barbara Schapira
openalex +1 more source
Measure of non-compactness and limiting interpolation with slowly varying functions
AbstractWe give estimates for the measure of non-compactness of an operator interpolated by the limiting methods involving slowly varying functions. As applications we establish estimates for the measure of non-compactness of operators acting between Lorentz–Karamata spaces.
Fernando Cobos +2 more
openaire +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Lp-improving measures on compact non-abelian groups [PDF]
Kathryn E. Hare
openalex +1 more source

