Results 81 to 90 of about 2,105,065 (292)

Measurement errors with low-cost citizen science radiometers [PDF]

, 2016
The KdUINO is a Do-It-Yourself buoy with low-cost radiometers that measure a parameter related to water transparency, the diffuse attenuation coefficient integrated into all the photosynthetically active radiation. In this contribution, we analyze the
Bardají, R., Piera Fernández, Jaume
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

A Hybrid Approach to Short-Term Load Forecasting Aimed at Bad Data Detection in Secondary Substation Monitoring Equipment

Sensors, 2018
Bad data as a result of measurement errors in secondary substation (SS) monitoring equipment is difficult to detect and negatively affects power system state estimation performance by both increasing the computational burden and jeopardizing the state ...
Pedro Martín, Guillermo Moreno, Francisco Javier Rodríguez, José Antonio Jiménez, Ignacio Fernández   +4 more
doaj   +1 more source

Violation of Leggett-Garg inequalities in quantum measurements with variable resolution and back-action

, 2012
Quantum mechanics violates Leggett-Garg inequalities because the operator formalism predicts correlations between different spin components that would correspond to negative joint probabilities for the outcomes of joint measurements.
Bednorz A, Calarco T, Hofmann H F, Holger F Hofmann, Iinuma M, Lund A P, Masataka Iinuma, Xu J-S, Yutaro Suzuki   +8 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Multiple robust estimation in high-dimensional data with outliers and measurement errors in covariates

上海师范大学学报. 自然科学版
This article is based on the original empirical likelihood function, introducing Huber function and weight function into the estimation equation of the constraint conditions, combining the empirical likelihood method with the robust estimation equation ...
SUN Zongren
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Back to the Future: Scientific Method and Science Reliability

Journal of Nature and Science of Medicine
We have worked in physics applied to medicine in the past 20 years. Many changes have happened during this period, and we are witnessing an epochal change in the approach to scientific research. What was clear 20 years ago has become opaque.
Ivan Corazza, Pier Luca Rossi
doaj   +1 more source

Panel Regression with Random Noise [PDF]

The paper explores the effect of measurement errors on the estimation of a linear panel data model. The conventional fixed effects estimator, which ignores measurement errors, is biased.
Gerd Ronning, Hans Schneeweiss
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source