Results 111 to 120 of about 1,797,247 (312)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

The joint NASA/Goddard-University of Maryland research program in charged particle and high energy photon detector technology [PDF]

open access: yes
Progress made in the following areas is discussed: low energy ion and electron experiments; instrument design for current experiments; magnetospheric measurement of particles; ion measurement in the earth plasma sheet; abundance measurement; X-ray data ...

core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Highly Controllable Fabrication of Gold Composite Nanostructures by Multiple Electroplating for High‐Performance Electrochemical and Raman Scattering Measurements

open access: yesSmall Structures
Morphology‐controlled nanostructures are important functional materials in multidisciplinary research fields, such as sensing, imaging, catalysis, and energy harvesting.
Shengsen Zhang   +3 more
doaj   +1 more source

Discussion: Measurement and Instrumentation [PDF]

open access: yesJournal of Physics: Conference Series, 2014
ANDREANI, CARLA   +9 more
openaire   +2 more sources

Development and test of a Microwave Ice Accretion Measurement Instrument (MIAMI) [PDF]

open access: yes
The development of an ice accretion measurement instrument that is a highly sensitive, accurate, rugged and reliable microprocessor controlled device using low level microwave energy for non-instrusive real time measurement and recording of ice growth ...
Magenheim, B., Rocks, J. K.
core   +1 more source

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