Results 121 to 130 of about 1,797,247 (312)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Numerical Prediction of Solid Particle Erosion in Jet Pumps Based on a Calibrated Model

open access: yesEnergies
Jet pumps are widely used in petrochemical processes, nuclear cooling, and wastewater treatment due to their simple structure, high reliability, and stable performance under extreme conditions. However, when transporting solid-laden two-phase flows, they
Xuanchen Wan   +5 more
doaj   +1 more source

Introduction to total- and partial-pressure measurements in vacuum systems [PDF]

open access: yes
An introduction to the fundamentals of total and partial pressure measurement in the vacuum regime (760 x 10 to the -16th power Torr) is presented.
Kern, F. A., Outlaw, R. A.
core   +1 more source

Development and validation of a new measurement instrument to assess internship experience of medical doctors in low-income and middle-income countries. [PDF]

open access: yesBMJ Glob Health, 2023
Zhao Y   +16 more
europepmc   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Path planning for manipulators based on the planar constraint RRT* algorithm

open access: yesScientific Reports
Path planning is crucial for automatic measurement to ensure a collision-free process for manipulators. However, the more complex the measurement environment, the more complex the path planning scheme is often required in order to meet the above ...
Minyue Li   +4 more
doaj   +1 more source

Design and applications of optical interferometers in astronomy Final report [PDF]

open access: yes
Interferometer application to optical instrument testing, double star separation measurements, and photoelectric techniques for stellar diameter ...
Fredrick, L. W.   +2 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

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