Results 101 to 110 of about 544,111 (317)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

The problem of applying modern uncertainty concepts to the measurement of instrument specific parameters

, 2006
This paper presents a number of problems that occur when applying the Guide to the Expression of Uncertainty in Measurement (GUM) to modern instruments.
Kulesza, Wlodek,, Lauber, A.,, Lauber, Alexander, Kulesza, W.J.,, Wirandi, J.,, Wirandi, Jenny,, Kulesza, Wlodek, Wirandi, Jenny   +7 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Centralized exhaust system simulation and parameter optimization

Scientific Reports
With the increase in high-rise buildings in cities, public flue exhaust systems have a direct impact on residential air quality and the living environment.
Mingming Lu, Qian Miao, Pengfei Zhang, Guangwei Sun, Mingyue Yang, Yao Zhao, Kai Zhang, Chong Wang, An-ran Wang, Tong-fu Zheng   +9 more
doaj   +1 more source

Simulation Analysis and Experimental Study of Pipeline Gas Resistance Modelling and Series Characteristics

Fluids
The principle of electro-analogy analysis treats a gas path structure as analogous to a circuit, offering significant potential for performance analysis in aerostatic systems. However, research on gas resistance remains in an early stage.
Shengzhe Ye, Xiaoyan Shen, Hao Zhang, Xintong Liu   +3 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Establishment of New Electro-encephalogram Measurement Technology by Integrating Virtual Instrument

, 2012
[[abstract]]In this research, a new electro-encephalogram measurement technique isdesigned and constructed. The structure of virtual instrument built by softwarepart, Lab-viewBhardware part, DAQ card and some external circuits are applied inthe ...
Yao, K. C. ; Chen, D. F. ; Lu, Chien-Yu; Shyr, W. J., Yao, Kai-chao; Chen, Der-Fa; Lu, Chien-Yu; Shyr, Wen-Jye   +1 more
core  

First quarter quality assurance report for True Geothermal Energy Company Monitoring Program, Kilauea Middle East Rift Zone, island of Hawaii : November 1, 1989 - January 31, 1990 [PDF]

, 1990
"The aerometric analyzer audit results were satisfactory. The sulfur dioxide (502) and hydrogen sulfide (H2S) analyzers meet the slope and intercept criteria.
Measurement Technologies
core  

Coagulation Characteristics of Nano-agglomerates in Free Molecular States under Different Electric Field Intensities

Aerosol and Air Quality Research
The coagulation behavior of nanoparticles in microfluidic chip channels is complex and affected by various external factors, including electric fields, sound fields, and wakes.
Ting Luo, Pengfei Zhang, Dongxu Cheng, Congcong Li, Junyi Shen, Mingyue Yang, Jie Zhao, Kai Zhang, Qianyuan Yu, Zhandong Shi   +9 more
doaj   +1 more source