Results 81 to 90 of about 506,486 (268)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

A Fuzzy-PI Clock Servo with Window Filter for Compensating Queue-Induced Delay Asymmetry in IEEE 1588 Networks

Sensors
Clock synchronization is one of the popular research topics in Distributed Measurement and Control Systems (DMCSs). In most industrial fields, such as Smart Grid and Flight Test, the highest requirement for synchronization accuracy is 1 μs.
Yifeng Zhang, Haotian Li, Shixuan Wang, Feifan Chen   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

LSA‐HELM: A Boosted Configuration to Optimize the Reconstruction Model of Dynamic Force on Aviation Composite Skin

IET Science, Measurement & Technology
The reconstruction of impact forces is critical for structural health monitoring of aero‐composite wings. However, due to its complex structure with a limited sensor array, the impact force cannot be accurately determined simply by using an equal‐weight ...
Chuansheng Huang, Wensong Jiang, Zai Luo, Xuan Wei, Li Yang, Siqi Feng, Siyuan Zhang, Zilu Zhang   +7 more
doaj   +1 more source

The Application of Piecewise Regularization Reconstruction to the Calibration of Strain Beams

Sensors
Standard beams are mainly used for the calibration of strain sensors using their load reconstruction models. However, as an ill-posed inverse problem, the solution to these models often fails to converge, especially when dealing with dynamic loads of ...
Jingjing Liu, Wensong Jiang, Zai Luo, Penghao Zhang, Li Yang, Yinbao Cheng, Dian Bian, Yaru Li   +7 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Simulation Analysis and Experimental Study of Pipeline Gas Resistance Modelling and Series Characteristics

Fluids
The principle of electro-analogy analysis treats a gas path structure as analogous to a circuit, offering significant potential for performance analysis in aerostatic systems. However, research on gas resistance remains in an early stage.
Shengzhe Ye, Xiaoyan Shen, Hao Zhang, Xintong Liu   +3 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Highly Controllable Fabrication of Gold Composite Nanostructures by Multiple Electroplating for High‐Performance Electrochemical and Raman Scattering Measurements

Small Structures
Morphology‐controlled nanostructures are important functional materials in multidisciplinary research fields, such as sensing, imaging, catalysis, and energy harvesting.
Shengsen Zhang, Shengjie Chen, Kunru Yu, Rong Zhu   +3 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source