Results 71 to 80 of about 481,743 (269)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

A Fuzzy-PI Clock Servo with Window Filter for Compensating Queue-Induced Delay Asymmetry in IEEE 1588 Networks

Sensors
Clock synchronization is one of the popular research topics in Distributed Measurement and Control Systems (DMCSs). In most industrial fields, such as Smart Grid and Flight Test, the highest requirement for synchronization accuracy is 1 μs.
Yifeng Zhang, Haotian Li, Shixuan Wang, Feifan Chen   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

LSA‐HELM: A Boosted Configuration to Optimize the Reconstruction Model of Dynamic Force on Aviation Composite Skin

IET Science, Measurement & Technology
The reconstruction of impact forces is critical for structural health monitoring of aero‐composite wings. However, due to its complex structure with a limited sensor array, the impact force cannot be accurately determined simply by using an equal‐weight ...
Chuansheng Huang, Wensong Jiang, Zai Luo, Xuan Wei, Li Yang, Siqi Feng, Siyuan Zhang, Zilu Zhang   +7 more
doaj   +1 more source

The Application of Piecewise Regularization Reconstruction to the Calibration of Strain Beams

Sensors
Standard beams are mainly used for the calibration of strain sensors using their load reconstruction models. However, as an ill-posed inverse problem, the solution to these models often fails to converge, especially when dealing with dynamic loads of ...
Jingjing Liu, Wensong Jiang, Zai Luo, Penghao Zhang, Li Yang, Yinbao Cheng, Dian Bian, Yaru Li   +7 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Simulation Analysis and Experimental Study of Pipeline Gas Resistance Modelling and Series Characteristics

Fluids
The principle of electro-analogy analysis treats a gas path structure as analogous to a circuit, offering significant potential for performance analysis in aerostatic systems. However, research on gas resistance remains in an early stage.
Shengzhe Ye, Xiaoyan Shen, Hao Zhang, Xintong Liu   +3 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Highly Controllable Fabrication of Gold Composite Nanostructures by Multiple Electroplating for High‐Performance Electrochemical and Raman Scattering Measurements

Small Structures
Morphology‐controlled nanostructures are important functional materials in multidisciplinary research fields, such as sensing, imaging, catalysis, and energy harvesting.
Shengsen Zhang, Shengjie Chen, Kunru Yu, Rong Zhu   +3 more
doaj   +1 more source