Results 131 to 140 of about 452,809 (247)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Assessment of eHealth Literacy in Healthcare Service Users: Construction and Validation of a Measurement Instrument. [PDF]

Clin Pract Epidemiol Ment Health
Morales J, Eguia CA.
europepmc   +1 more source

[Spatiotemporal psychopathology-German version of the Scale for Space and Time Experience in Psychosis (STEP) : A validated measurement instrument for the assessment of spatial and temporal experience in psychotic disorders]. [PDF]

Nervenarzt, 2023
Hirjak D, Daub J, Brandt GA, Krayem M, Kubera KM, Northoff G.   +5 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Correction: Disaster health literacy - development and validation of a short measurement instrument in German to supplement the HLS₁₉ instruments. [PDF]

Front Public Health
Ewers M, Beckert J, Griese L, Köhler M, Prasser A, Singh H, Schaeffer D.   +6 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Disaster Health Literacy - development and validation of a short measurement instrument in German to supplement the HLS₁₉ instruments. [PDF]

Front Public Health
Ewers M, Beckert J, Griese L, Köhler M, Prasser A, Singh H, Schaeffer D.   +6 more
europepmc   +1 more source

On the modelling and testing of a laboratory-scale Foucault pendulum as a precursor for the design of a high-performance measurement instrument. [PDF]

Proc Math Phys Eng Sci, 2020
Cartmell MP, Faller JE, Lockerbie NA, Handous E.   +3 more
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Development and validation of a measurement instrument for physical activity-related health literacy (PA-HL): a study protocol. [PDF]

Arch Public Health
Fitzner E, Hering T, Dadaczynski K.
europepmc   +1 more source