Results 231 to 240 of about 2,250,709 (315)

Estimation of Weight and Body Measurement Model for Pigs Based on Back Point Cloud Data. [PDF]

Animals (Basel)
Liu Y, Zhou J, Bian Y, Wang T, Xue H, Liu L.   +5 more
europepmc   +1 more source

A Country Pandemic Risk Exposure Measurement Model. [PDF]

Risk Manag Healthc Policy, 2020
Grima S, Kizilkaya M, Rupeika-Apoga R, Romānova I, Dalli Gonzi R, Jakovljevic M.   +5 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Power analyses for measurement model misspecification and response shift detection with structural equation modeling. [PDF]

Qual Life Res
Verdam MGE.
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Estimation of Respiratory States Based on a Measurement Model of Airflow Characteristics in Powered Air-Purifying Respirators Using Differential Pressure and Pulse Width Modulation Control Signals-In the Development of a Public-Oriented Powered Air-Purifying Respirator as an Alternative to Lockdown Measures. [PDF]

Sensors (Basel)
Fujii Y, Takita A, Hashimoto S, Amagai K.   +3 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

The Dynamic Measurement-Burst Model: A method for assessing psychological process features at multiple timescales.

Longitudinal research in psychology has traditionally been approached with an either-or attitude: Either we are able to study momentary dynamics of psychological processes using intensive longitudinal data (ILD), or we are able to study individual ...
Ellen Hamaker, Noémi Katalin Schuurman, Pia K. Andresen   +2 more
core  

The reflective measurement model of adherence to non-pharmaceutical interventions (NPIs) in accordance with normalization process theory (NPT) in coherent and convenient social subgroups: PLS-SEM analysis. [PDF]

Eur J Public Health
Pletikosa Pavic M, Pranic SM, Mastelic T, Kljucevic Z, Gotovac M, Savicevic AJ, Kozina T, Kozina S.   +7 more
europepmc   +1 more source

A Measurement Model of Mutual Influence for Information Dissemination. [PDF]

Entropy (Basel), 2020
Zhang L, Quan Y, Zhou B, Jia Y, Gao L.
europepmc   +1 more source