Results 91 to 100 of about 3,371,459 (278)

Crack propagation in light alloys Ministry of Aviation contract no. PD/28/07 [PDF]

, 1965
The revised approach to the measurement of the rate of crack propagation in light alloys has entailed the development of new experimental techniques, in particular the development of a multi-channel interval timer.
Younger, A.
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Modulating SARS-CoV‑2 Spike Protein Reactivity through Moderate Electric Fields: A Pathway to Innovative Therapies

ACS Omega, 2023
Thi-Huong Nguyen, Hanqing Wang, Li-Yu Chen, Danny Echtermeyer, Uwe Pliquett   +4 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Dynamic cell culture modulates colon cancer cell migration in a novel 3D cell culture system

Scientific Reports
The progression of cancer cell migration, invasion and subsequent metastasis is the main cause of mortality in cancer patients. Through creating more accurate cancer models, we can achieve more precise results, which will lead to a better understanding ...
M. Mohamadian Namaqi, F. Moll, S. Wiedemeier, A. Grodrian, K. Lemke   +4 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Adaptive particle image velocimetry based on sharpness metrics

Journal of the European Optical Society-Rapid Publications, 2018
Background Optical distortions can significantly deteriorate the measurement accuracy in particle image velocimetry systems. Such distortions can occur at fluctuating phase boundaries during flow measurement and result from the accompanied refractive ...
M. Teich, J. Grottke, H. Radner, L. Büttner, J. W. Czarske   +4 more
doaj   +1 more source

Thermal resistance measurement techniques study program Final report [PDF]

Thermal resistance measurement technique development for ...
Davidson, K. W., Greer, P. H.
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Development of heat flux sensors in turbine airfoils [PDF]

, 1984
The objective is to develop heat flux sensors suitable for use on turbine airfoils and to verify the operation of the heat flux measurement techniques through laboratory experiments.
Atkinson, W. H., Strange, R. R.
core   +1 more source