Results 71 to 80 of about 8,352,378 (305)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

4. Workshop - Measurement techniques of stationary and transient multiphase flow

, 2001
In November 2000, the 4th Workshop on Measurement Techniques for Stationary and Transient Multiphase Flows took place in Rossendorf. Three previous workshops of this series were national meetings; this time participants from different countries took part.
Prasser, H.M. (ed.), Forschungszentrum Rossendorf e.V. (FZR), Dresden (Germany)   +1 more
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

PERFORMANCE COMPARISON OF DIFFERENT TECHNIQUES FOR AVAILABLE BANDWIDTH MEASUREMENT IN PACKET-SWITCHED NETWORKS

, 2003
As variety of applications and services that can be provided on packet switched networks has strongly increased over the last years and keeps on increasing, the need for an accurate network monitoring has become an important challenge to be dealt with ...
ANGRISANI, LEOPOLDO, D'ANTONIO, Salvatore, VADURSI, Michele, VENTRE, GIORGIO, Angrisani, L., S. D'ANTONIO, M. VADURSI, Ventre, G.   +7 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Phase preservation of orbital angular momentum of light in multiple scattering environment

Light: Science & Applications
Recent advancements in wavefront shaping techniques have facilitated the study of complex structured light’s propagation with orbital angular momentum (OAM) within various media.
Igor Meglinski, Ivan Lopushenko, Anton Sdobnov, Alexander Bykov   +3 more
doaj   +1 more source

Using Auto-ML on Synthetic Point Cloud Generation

Applied Sciences
Automated Machine Learning (Auto-ML) has primarily been used to optimize network hyperparameters or post-processing parameters, while the most critical component for training a high-quality model, the dataset, is usually left untouched. In this paper, we
Moritz Hottong, Moritz Sperling, Christoph Müller   +2 more
doaj   +1 more source

Measurement of the Local Sound Pressure on a Bias-Flow Liner Using High-Speed Holography and Tomographic Reconstruction

IEEE Access, 2019
Bias-flow liners (BFL) are used as part of the cooling mechanism in airplane turbines and they also enable the reduction of noise emission. The attenuating principle is based on the interaction between sound waves and air flow.
Andres E. Ramos Ruiz, Johannes Gurtler, Robert Kuschmierz, Jurgen W. Czarske   +3 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source