Results 61 to 70 of about 1,084,034 (311)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Flexible Toolbox of High-Precision Microfluidic Modules for Versatile Droplet-Based Applications
Although the enormous potential of droplet-based microfluidics has been successfully demonstrated in the past two decades for medical, pharmaceutical, and academic applications, its inherent potential has not been fully exploited until now. Nevertheless,
Mario Saupe +4 more
doaj +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
As variety of applications and services that can be provided on packet switched networks has strongly increased over the last years and keeps on increasing, the need for an accurate network monitoring has become an important challenge to be dealt with ...
ANGRISANI, LEOPOLDO +7 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
An Empirical Survey of Frontier Efficiency Measurement Techniques in Education
Educational institutions worldwide are increasingly the subject of analyses aimed at defining, measuring and improving efficiency. However, despite the importance of efficiency measurement in education, it is only relatively recently that the more ...
Worthington, Andrew C. +1 more
core +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
4. Workshop - Measurement techniques of stationary and transient multiphase flow
In November 2000, the 4th Workshop on Measurement Techniques for Stationary and Transient Multiphase Flows took place in Rossendorf. Three previous workshops of this series were national meetings; this time participants from different countries took part.
Prasser, H.M. (ed.) +1 more
core
Oxidation of sulfur dioxide (SO2) in the gas phase and in cloud and fog water leads to the formation of sulfate that contributes to ambient particulate matter (PM). For severe haze events with low-light conditions, current models underestimate the levels
Kroll, Jesse +5 more
core +1 more source
Techniques for the Measurement of Molecular Species of Acyl-CoA in Plants and Microalgae
The acyl-CoA pool is pivotal in cellular metabolism. The ability to provide reliable estimates of acyl-CoA abundance and distribution between molecular species in plant tissues and microalgae is essential to our understanding of lipid metabolism and acyl
Larson, T. R. +3 more
core +1 more source

