Results 151 to 160 of about 8,352,378 (305)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Evaluating Variability in Extracellular Vesicle Characterization Across Measurement Techniques. [PDF]

J Extracell Biol
Singh PK, Usmani AF, Halder D, Miller J, Kanagasabai T, Sarchet P, Weller K, Klarmann GJ, Pollock RE, Calore F, Prakash S.   +10 more
europepmc   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

A multi-utility smart metering architecture to improve energy efficiency

, 2015
Smart meters are essential tools to increase energy efficiency of buildings and grid. However, to get a real benefit from them, an effective integration between the different energy domestic metering devices and display, as well as a suitable post ...
Betta, G., Celenza, L., Dell'Isola, M., Ficco, Giorgio, Ferrigno, L., Dell'Isola, Marco, Ferrigno, Luigi, Ficco, G., Capriglione, D., CAPRIGLIONE, Domenico, Betta, Giovanni   +10 more
core  

Comparative Analysis of Work Function Measurement Techniques Based on Scanning Probe Microscopy. [PDF]

Adv Mater
Alamdary DN, Bode M, Odobesko A.
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

A comparison of inequality measurement techniques [PDF]

There are numerous statistical techniques designed for the measurement of inequality. Each individual index has a unique set of properties which can make the choice of an appropriate measure difficult.
Nicholas Rohde
core  

Electron transport reactions of cyanobacterial photosynthesis and state-of-the-art in vivo measurement techniques. [PDF]

Plant Physiol
Wey LT, Bos PR, Crosbie M, Ortega Martínez P, Tiwari A, Nikkanen L.   +5 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Mechanobiology of the tumor microenvironment: a review of therapeutic interactions and in vitro elasticity measurement techniques. [PDF]

J Biomed Sci
Chen TW, Yu SH, Lu SL, Yeh CH, Li PC.
europepmc   +1 more source