Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Advanced optical measurement techniques for simultaneous fibre orientation and flow analysis complemented by machine learning. [PDF]
Vaupel T +3 more
europepmc +1 more source
Reliability of new radiographic measurement techniques for elbow bony impingement. [PDF]
Meglic U, Zupanc O.
europepmc +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Instruments and Measurement Techniques to Assess Extremely Low-Frequency Electromagnetic Fields. [PDF]
Rathebe PC, Kholopo M.
europepmc +1 more source
Comparing MRI volume measurement techniques for pituitary macroadenoma: Investigating volume reduction and its relationship with biochemical control. [PDF]
Hussein IH, Mansour AA, Jameel NA.
europepmc +1 more source
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
A Review of Pore Water Pressure Measurement Techniques in Early-Age Cement-Based Materials. [PDF]
Tian Q, Wang Y, Li H, Wang Y, Jiang C.
europepmc +1 more source
Residual Stress Measurement Techniques for Metal Joints, Metallic Coatings and Components in the Railway Industry: A Review. [PDF]
Kendall O +6 more
europepmc +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source

