Results 31 to 40 of about 1,342,843 (277)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

How to Save You Skin When Processing L2 Idioms: An Eye Movement Analysis of Idiom Transparency and Cross-language Similarity among Bilinguals [PDF]

Iranian Journal of Language Teaching Research, 2017
The current study looks at whether bilinguals varying in language dominance show a processing advantage for idiomatic over non-idiomatic phrases and to what extent this effect is modulated by idiom transparency (i.e., the degree to which the idiom’s ...
Anna Cieślicka, Roberto R. Heredia
doaj  

What matters most to patients following percutaneous coronary interventions? A new patient-reported outcome measure developed using Rasch analysis.

PLoS ONE, 2019
IntroductionMeasuring patient reported outcomes can improve the quality and effectiveness of healthcare interventions. The aim of this study was to identify the final set of items that can be included in a patient-reported outcome measure to assess ...
Sze-Ee Soh, Anna L Barker, Darshini R Ayton, Susannah Ahern, Renata Morello, Jeffrey Lefkovits, Angela L Brennan, Susan Evans, John R Zalcberg, Christopher M Reid, John J McNeil   +10 more
doaj   +1 more source

Effective Pre-school and Primary Education Project 3-11 (EPPE 3-11): the effectiveness of primary schools in England in Key Stage 2 for 2002, 2003 and 2004. [PDF]

, 2006
This report covers children\u27s progress during Key Stage 2 in all primary schools in England over a three year period (2002-2004). Value added multilevel models are used to investigate children\u27s progress in Key Stage 2 by controlling for prior ...
Melhuish, Edward, Romaniuk, Helena, Sammons, Pam, Siraj-Blatchford, Iram, Sylva, Kathy, Taggart, Brenda   +5 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Reading the International Fruit Company Saga More than 50 Years Later: At the Intersection of the ‘Common’ Market, Agricultural Policy and Commercial policy

European Papers
(Series Information) European Papers - A Journal on Law and Integration, 2026 11(1), 171-193 | Article | (Table of Contents) 1. Introduction. – 2. The legal and historical context of the International Fruit Company saga at the Community and international
Silvia Giudici
doaj   +1 more source

Neighbourhood socioeconomic inequalities in incidence of acute myocardial infarction: a cohort study quantifying age- and gender-specific differences in relative and absolute terms

BMC Public Health, 2012
Background Socioeconomic status has a profound effect on the risk of having a first acute myocardial infarction (AMI). Information on socioeconomic inequalities in AMI incidence across age- gender-groups is lacking.
Koopman Carla, van Oeffelen Aloysia AM, Bots Michiel L, Engelfriet Peter M, Verschuren WM, van Rossem Lenie, van Dis Ineke, Capewell Simon, Vaartjes Ilonca   +8 more
doaj   +1 more source

Impacts of EU Tobacco Products Directive regulations on use of e-cigarettes in adolescents in Great Britain: a natural experiment evaluation

Public Health Research, 2023
Background E-cigarettes are a popular smoking-cessation tool. Although less harmful than tobacco, use of e-cigarettes by non-smokers should be prevented. There is concern about the use of e-cigarettes by young people and that e-cigarettes may renormalise
Moore Graham, Hallingberg Britt, Brown Rachel, McKell Jennifer, Van Godwin Jordan, Bauld Linda, Gray Linsay, Maynard Olivia, Mackintosh Anne-Marie, Munafò Marcus, Blackwell Anna, Lowthian Emily, Page Nicholas   +12 more
doaj   +1 more source

Of Trailers and Jet Skis: Is the Case Law on Article 34 TFEU Hurtling in a New Direction? [PDF]

, 2006
The provision which is the focus of this Article is article 34 of the Treaty on the Functioning of the European Union ( TFEU or Treaty ) (formerly article 28 EC).
Oliver, Peter
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source