Results 41 to 50 of about 16,963,019 (272)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Densities generated by equivalent measures
, 2011 In the family of all measures equivalent to the Borel measure µ defined in a metric space X, we look for measures generating the same density points (preserving µ-density at fixed point x 0 ∈ X).
Tadeusz Poreda +2 more
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Optimal Equivalent Probability Measures under Enlarged Filtrations
, 2018 In a general jump-diffusion Radon–Nikodym setup with stochastic Girsanov processes, we derive optimal equivalent probability measures. Optimality is measured in terms of minimum relative entropy and also by more general divergence concepts.
Markus Hess, Hess, Markus
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Role of eperisone as an oral analgesic adjunct after arthroscopic rotator cuff repair
Journal of Orthopaedic ReportsBackground: Inadequate pain relief during the early post-operative stages following arthroscopic shoulder procedures may lead to patients having poor functional and satisfaction outcomes.
Cheryl Gatot +4 more
doaj +1 more source
Neurobehavioral response to increased treatment dosage in chronic, severe aphasia
Frontiers in Psychology, 2014 Introduction Intensive aphasia treatment has been employed with equivocal results likely due in part to variability in the severity of participants as well as in the parameters that comprise intensity (e.g., session duration).
Jennifer L Mozeiko, Emily B. Myers
doaj +1 more source
Algebraic Numbers and Topologically Equivalent Measures [PDF]
, 1983 A set-theoretical point of view to study algebraic numbers has been introduced. We extend a result of Navarro-Bermudez concerning shift invariant measures in the Cantor space which are topologically equivalent to shift invariant measures which correspond
Huang, Kuoduo
core
Comparison between SuperDARN flow vectors and equivalent ionospheric currents from ground magnetometer arrays [PDF]
, 2012 Equivalent ionospheric currents obtained with the spherical elementary current systems (SECS) method and derived from nearly 100 ground magnetometers spread over North America and Greenland are compared with ionospheric flow vectors measured by the ...
Angelopoulos, V. +6 more
core +3 more sources