Results 31 to 40 of about 616,302 (291)

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Expanding the Application of Threonine: Industrial Biomanufacturing of Threonine and Its Derivatives

Fermentation
Currently, the production methods for L-threonine (L-Thr) mainly include chemical synthesis, protein hydrolysis, and microbial fermentation. Among these, microbial fermentation has become an important method for the industrial production of L-Thr, owing ...
Liwen Lu, Lin Su, Qingjing Huang, Xiao Zou, Bangmeng Zhou, Jun Kang, Yang Li, Jiamin Zhang, Jie Cheng   +8 more
doaj   +1 more source

Microstructure Reconstruction in Battery Electrodes Using Machine Learning Based on Low‐Voltage Focused Ion Beam–Scanning Electron Microscopy Tomography Images

Advanced Engineering Materials, EarlyView.
Low‐voltage FIB‐SEM tomography combined with a image preprocessing pipeline improves phase contrast and enables reliable machine‐learning segmentation of conductive networks in lithium‐ion battery electrodes. Structural descriptors are extracted from segmented images, done semimanually and automated, and compared.
Lisa Beran, Vincent Nebel, Dominik Perius, Kshitij Kumar, Yannis Heim, Laura Bies, Tobias Kraus   +6 more
wiley   +1 more source

Strategies for enhancing protein solubility: methods, applications, and prospects

npj Science of Food
Controlling protein solubility is critical yet challenging for food and pharmaceutical applications. This review dissects the molecular and environmental determinants governing solubility behavior.
Ruiqi Cao, Weihao Wang, Zhiyan Zhang, Chuan Wang, Qingjing Huang, Lixiu Yan, Jiamin Zhang, Jie Cheng   +7 more
doaj   +1 more source

Enhancing Caffeic Acid Production in Escherichia coli Through Heterologous Enzyme Combinations and Semi-Rational Design

Metabolites
Background/Objectives: Caffeic acid is a hydroxycinnamic acid that has a wide range of applications in the medical field. The synthesis of caffeic acid using microbial fermentation technology is an environmentally friendly method.
Qing Luo, Weihao Wang, Qingjing Huang, Chuan Wang, Lixiu Yan, Jun Kang, Jiamin Zhang, Jie Cheng   +7 more
doaj   +1 more source

Odor Emissions from Raw Meat of Freshly Slaughtered Cattle during Inspection

Foods, 2021
Raw meat of Freshly Slaughtered Cattle (FSC) is characterized by a very weak odor defined as slightly sweet, which could interfere in off-odor assessment during post-mortem inspection by an official veterinarian.
Francesca Conte, Fabrizio Cincotta, Concetta Condurso, Antonella Verzera, Antonio Panebianco   +4 more
doaj   +1 more source

Additional post-mortem inspection procedures and laboratory methods as supplements for visual meat inspection of finishing pigs in Europe—Use and variability [PDF]

, 2022
In the EU, a post-mortem inspection of finishing pigs comprises visual inspections of the carcass and offal followed by additional examinations, such as palpation and incision of parts, when needed.
Gómez Laguna, Jaime, Lis Alban, Langkabel, Nina, Patric Maurer, Sergio Ghidini, Alvseike, Ole, Meemken, Diana, Laukkanen-Ninios, Riikka, Riikka Laukkanen-Ninios, Jaime Gómez Laguna, Ghidini, Sergio, Madalena Vieira-Pinto, Santos, Susana, Nina Langkabel, Diana Meemken, Vieira-Pinto, Madalena, Maurer, Patric, Alban, Lis, Susana Santos, Ole Alvseike   +19 more
core   +1 more source

A Practical Noise2Noise Denoising Pipeline for High‐Throughput Raman Spectroscopy

Advanced Engineering Materials, EarlyView.
A lightweight and reproducible denoising pipeline for high‐throughput Raman spectroscopy is introduced, based on a 1D convolutional autoencoder trained with a Noise2Noise strategy. Using only repeated short‐exposure acquisitions, the method suppresses stochastic noise without reference spectra, enabling reliable spectral reconstruction while preserving
David Martin‐Calle, Cesar Alvarez‐Llamas, Vincent Motto‐Ros, Christophe Dujardin, Jérémie Margueritat, David Rodney   +5 more
wiley   +1 more source

Using Pathogenic Escherichia coli Type III Secreted Effectors espK and espV as Markers to Reduce the Risk of Potentially Enterohemorrhagic Shiga Toxin-Producing Escherichia coli in Beef

Foods
Contamination of beef by certain strains of Shiga toxin-producing Escherichia coli (STEC) called enterohemorrhagic E. coli (EHEC) can lead to outbreaks of severe disease. Therefore, accurate monitoring tests are needed to identify high risk beef products
Joseph M. Bosilevac, Tatum S. Katz, Leslie E. Manis, Lorenza Rozier, Michael Day   +4 more
doaj   +1 more source

Diagnostic efficiency of abattoir meat inspection service in Ethiopia to detect carcasses infected with Mycobacterium bovis: Implications for public health

BMC Public Health, 2010
Background Bovine Tuberculosis (BTB) is a widespread and endemic disease of cattle in Ethiopia posing a significant threat to public health. Regular surveillance by skin test, bacteriology and molecular methods is not feasible due to lack of resource ...
Bogale Asseged, Biffa Demelash, Skjerve Eystein   +2 more
doaj   +1 more source