Results 161 to 170 of about 899,308 (256)

Transient mechanical activation of the Piezo1 channel facilitates ex vivo expansion of hematopoietic stem cells. [PDF]

Cell Res
Wang Q, Zeng X, Yang H, Lu H, Jiang L, Xu L, Li J, Li J, Han Y, Wu X, Zhou Y, Chen X, Zhao Y, Shi J, Luo Y, Ni F, Sun J, Zhao Q, Yang F, Xia P, Jiang H, Huang H, Qian P.   +22 more
europepmc   +1 more source

Multistage Mechanical Activation of Multilayer Carbon Nanotubes in Creation of Electric Heaters with Self-Regulating Temperature. [PDF]

Materials (Basel), 2021
Shchegolkov AV, Jang SH, Shchegolkov AV, Rodionov YV, Glivenkova OA.   +4 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Enhanced Leaching of Lepidolite by Acidophilic Microorganisms Under Mechanical Activation. [PDF]

Microorganisms
Li J, Wang M, Zhang R, Liu H, Huang S, Liu Y, Liao R, Vardanyan A, Xia J, Wang J.   +9 more
europepmc   +1 more source

Targeting the latest site of left ventricular mechanical activation is associated with improved long-term outcomes for recipients of cardiac resynchronization therapy. [PDF]

Heart Rhythm O2, 2022
Borgquist R, Barrington WR, Bakos Z, Werther-Evaldsson A, Saba S.   +4 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Mechanical Activation of cPLA2 Impedes Fatty Acid β-Oxidation in Vein Grafts. [PDF]

Adv Sci (Weinh)
Fan L, Tang Y, Liu J, Liu Y, Xu Y, Liu J, Liu H, Pang W, Guo Y, Yao W, Zhang T, Peng Q, Zhou J.   +12 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

SCAR-AWARE LATE MECHANICAL ACTIVATION DETECTION NETWORK FOR OPTIMAL CARDIAC RESYNCHRONIZATION THERAPY PLANNING. [PDF]

Proc IEEE Int Symp Biomed Imaging
Xing J, Wang S, Patel AR, Bilchick KC, Epstein FH, Zhang M.   +5 more
europepmc   +1 more source

Mechanical activation of the angiotensin II type 1 receptor contributes to abdominal aortic aneurysm formation. [PDF]

JVS Vasc Sci, 2021
Hall S, Ward ND, Patel R, Amin-Javaheri A, Lanford H, Grespin RT, Couch C, Xiong Y, Mukherjee R, Jones JA, Ruddy JM.   +10 more
europepmc   +1 more source