Results 161 to 170 of about 915,324 (354)

A modular spring-loaded actuator for mechanical activation of membrane proteins. [PDF]

Nat Commun, 2022
Mills A, Aissaoui N, Maurel D, Elezgaray J, Morvan F, Vasseur JJ, Margeat E, Quast RB, Lai Kee-Him J, Saint N, Benistant C, Nord A, Pedaci F, Bellot G.   +13 more
europepmc   +1 more source

Mechanical Properties and Microstructure Improvement of a Two-Step Strain Induced Melt Activation Processed 7075 Aluminum Alloy Compared to that SIMA Process

, 2017
Mostafa Karamouz, Mostafa Alizadeh, Ali Ahmadi   +2 more
openalex   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Mechanical Activation of Forbidden Photoreactivity in Oxa-di-π-methane Rearrangement. [PDF]

J Org Chem, 2022
Jodra A, García-Iriepa C, Frutos LM.
europepmc   +1 more source

Stretch-elicited Na+/H+ exchanger activation: the autocrine/paracrine loop and its mechanical counterpart [PDF]

, 2003
Horacio E. Cingolani
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

A mathematical model for mechanical activation and compound action potential generation by the utricle in response to sound and vibration. [PDF]

Front Neurol, 2023
Pastras CJ, Gholami N, Jennings S, Zhu H, Zhou W, Brown DJ, Curthoys IS, Rabbitt RD.   +7 more
europepmc   +1 more source

Mechanical stress determines the configuration of TGFβ activation in articular cartilage [PDF]

, 2021
Gehua Zhen, Qiaoyue Guo, Yusheng Li, Chuanlong Wu, Shouan Zhu, Ruomei Wang, X. Edward Guo, Byoung Choul Kim, Jessie Huang, Yizhong Hu, Yang Dan, Mei Wan, Taekjip Ha, Steven S. An, Xu Cao   +14 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Effect of Mechanical Activation and High Pressure High Temperature Treatment on Synthesis of Material Based on Nanostructured Boron Nitride

Механика машин, механизмов и материалов, 2019
In the paper, the study of the influence of mechanical activation (MA) and subsequent high pressure high temperature (HPHT) treatment of the powder of hexagonal boron nitride (hBN) on its structure and phase composition is given.
Vladimir T. Senyut, Svetlana A. Kovaliova, Igor V. Val’kovich , Viktor I. Zhornik, Wensheng Li, Cheng Bo, Dongqing He , Haimin Zhai   +7 more
doaj