Results 11 to 20 of about 4,244,892 (203)

A Two-Step Baro-Mechanical Cycle for Repeated Activation and Deactivation of Mechanophores [PDF]

, 2021
Mechanophores that are embedded in a polymer backbone respond to the application of mechanical stretching forces by geometric changes such as bond rupture. Typically, these structural changes are irreversible, which limits the applicability of functional
Felix, Zeller, Sourabh, Kumar, Tim, Stauch   +2 more
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Mechanical muscle properties and intermuscular coordination in maximal and submaximal cycling: theoretical and practical implications [PDF]

, 2014
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel UniversityThe ability of an individual to perform a functional movement is determined by a range of mechanical properties including the force and power producing ...
Barratt, Paul
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Effect of the mechanical activation on size reduction of crystalline acetaminophen drug particles [PDF]

, 2009
The decrease in particle size may offer new properties to drugs. In this study, we investigated the size reduction influence of the acetaminophen (C8H9O2N) particles by mechanical activation using a dry ball mill.
Asefnejad, Azadeh, Zeinali, Reza, Ardeshir, Mahmoud, Biazar, Esmaeil, Sahebalzamani, Ali, Heidari, Majid, Forati, Tahmineh, Beitollahi, Ali, Rahimi, Mehdi, Rezayat, S Mehdi, Hatamjafari, Farhad   +10 more
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Investigating mechanosensitive channels activation in concert with the mechanical properties of red blood cells [PDF]

, 2023
The activity of the mechanosensitive Ca2+ permeable channels expressed in the membrane of the red blood cells (RBC) is determined both by the mechanical stimuli and the mechanical properties of the cell.
Catalin Dacian Ciubotaru, Annalisa Bernareggi, Bernareggi, Annalisa, Davide Rizzo, Lorenzo Bergamo, Nicoletta Braidotti, Ciubotaru, Catalin Dacian, Cojoc, Dan, Braidotti, Nicoletta, Rizzo, Davide, Dan Cojoc, Bergamo, Lorenzo   +11 more
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Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation [PDF]

, 2014
The force-dependent interaction between talin and vinculin plays a crucial role in the initiation and growth of focal adhesions. Here we use magnetic tweezers to characterise the mechano-sensitive compact N-terminal region of the talin rod, and show that
J. Yan (3377042), 陈虎, Yan, Jie, Sheetz, M.P., M. Yao (5803124), Cong, Peiwen, Yao, M, Goult, Benjamin T., Chen, H, Cong, P, Cong, P., Sheetz, Michael P., Goult, Benjamin T, M. P. Sheetz (7676465), Goult, BT, Sheetz, Michael P, Yan, J., P. Cong (7676462), Sheetz, MP, H. Chen (1500661), Yan, J, Goult, B.T., Chen, H., Yao, Mingxi, Chen, Hu, Yao, M., Benjamin T. Goult (173495)   +26 more
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Molecular brakes regulating mTORC1 activation in skeletal muscle following synergist ablation [PDF]

, 2014
The goal of the current work was to profile positive (mTORC1 activation, autocrine/paracrine growth factors) and negative [AMPK, unfolded protein response (UPR)] pathways that might regulate overload-induced mTORC1 activation with the hypothesis that a ...
Hamilton, D. Lee, Gallagher, Iain J, Philp, A., Baar, Keith, Towler, Mhairi C., Bodine, S. C., Gallagher, Iain J., Philp, Andrew, Towler, M. C., Baar, K., Towler, Mhairi C, Mackenzie, M. G., Gallagher, I. J., Patton, Amy, Hamilton, David Lee, Patton, A., MacKenzie, Matthew G., Lee Hamilton, D., Bodine, Sue C, Bodine, Sue C., MacKenzie, Matthew G   +20 more
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Soluble epoxide hydrolase limits mechanical hyperalgesia during inflammation [PDF]

, 2011
Background Cytochrome-P450 (CYP450) epoxygenases metabolise arachidonic acid (AA) into four different biologically active epoxyeicosatrienoic acid (EET) regioisomers.
Geisslinger, Gerd, Gerd Geisslinger, Brandes, Ralf P., Brandes, Ralf, Michael J Fischer, Fleming, Ingrid, Scholich, Klaus, Woolf Clifford J, Ralf P Brandes, Clifford J Woolf, Fleming Ingrid, Reeh, Peter Werner, Brenneis Christian, Fischer, Michael, Coste Ovidiu, Coste, Ovidiu, Brandes Ralf P, Kai Altenrath, Reeh Peter W, Christian Brenneis, Scholich Klaus, Sisignano, Marco, Reeh, Peter W., Altenrath Kai, Ingrid Fleming, Peter W Reeh, Woolf, Clifford J., Angioni Carlo, Geisslinger Gerd, Angioni, Carlo Federico, Klaus Scholich, Brenneis, Christian, Ovidiu Coste, Carlo Angioni, Sisignano Marco, Marco Sisignano, Fischer, Michael J., Fischer Michael J, Altenrath, Kai, Angioni, Carlo   +39 more
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Mechanical activation influence on the morphological properties of La[2]O[3]-TiO[2]-B [PDF]

, 2016
The influence of mechanical activation of the powder mixture used to obtain the high-perfomance cathode for accelerating engineering with the SHS-method has been explored. The mechanically processed mixtures have been morphologically analyzed.
Zakusilov, Vladislav Vladimirovich, Pimenov, N., Chursin, Stanislav Sergeevich, Dolmatov, Oleg Yurevich, Kuznetsov, Mikhail Sergeyevich   +4 more
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New bonded assembly configuration for dynamic mechanical analysis of adhesives [PDF]

, 2013
A new sample configuration has been developed in order to study molecular mobility of an adhesive in a bonded assembly configuration by dynamic mechanical analysis.
Tonon, Claire, Chevalier, Mathieu, Combes, Hélène, Dantras, Eric, Lacabanne, Colette, Quiroga Cortes, Luis, Guigue, Pascale, Caussé, Nicolas   +7 more
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Paths reunited: initiation of the classical and lectin pathways of complement activation [PDF]

, 2010
Understanding the structural organisation and mode of action of the initiating complex of the classical pathway of complement activation (C1) has been a central goal in complement biology since its isolation almost 50 years ago.
Schmid, Ralf, Schwaeble, Wilhelm J., Wilhelm J. Schwaeble, Anthony H. Keeble, Russell Wallis, Mitchell, Daniel A., Keeble, Anthony H., Wallis, Russell, Ralf Schmid, Daniel A. Mitchell   +9 more
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