Results 21 to 30 of about 4,244,892 (203)

Study of alkaline hydrothermal activation of belite cements by thermal analysis [PDF]

, 2010
The effect of alkaline hydrothermal activation of class-C fly ash belite cement was studied using thermal analysis (TG/DTG) by determining the increase in the combined water during a period of hydration of 180 days.
Guerrero Bustos, Ana María, Goñi Elizalde, Sara, Guerrero Bustos, Ana   +2 more
core   +1 more source

Primary cilia disassembly down regulates mechanosensitive hedgehog signalling: a feedback mechanism controlling ADAMTS-5 expression in chondrocytes [PDF]

, 2014
SummaryObjectiveHedgehog signalling is mediated by the primary cilium and promotes cartilage degeneration in osteoarthritis. Primary cilia are influenced by pathological stimuli and cilia length and prevalence are increased in osteoarthritic cartilage ...
Knight, M.M., Chapple, JP, Chapple, J.P., Knight, MM, Thompson, CL, Thompson, C.L.   +5 more
core   +1 more source

Mechanical influence of tissue scaffolding design with different geometries using finite element study [PDF]

, 2023
The mechanical properties of tissue scaffolds are essential in providing stability for tissue repair and growth. Thus, the ability of scaffolds to withstand specific loads is crucial for scaffold design.
Roy, Sandipan, Faraji, Foad; id_orcid, Xinyi An, Zohourkari, Iman, Faraji, Foad, Mohammad Hossein Yazdi, Iman Zohourkari, Yazdi, Mohammad Hossein, Merdji, Ali, Moey, Lip Kean, Gnanasagaran, Constance Linda, An, Xinyi, Perk Lin Chong, Foad Faraji, Sandipan Roy, Constance Linda Gnanasagaran, Lip Kean Moey, Chong, Perk Lin, Ali Merdji, Zohourkari , Iman   +19 more
core   +1 more source

Determination of cellular strains by combined atomic force microscopy and finite element modeling [PDF]

, 2002
Many organs adapt to their mechanical environment as a result of physiological change or disease. Cells are both the detectors and effectors of this process.
Charras, GT, Charras, Guillaume T., Horton, MA, Horton, Mike A.   +3 more
core   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

The activation of IgM- or isotype-switched IgG- and IgE-BCR exhibits distinct mechanical force sensitivity and threshold

, 2015
B lymphocytes use B cell receptors (BCRs) to sense the physical features of the antigens. However, the sensitivity and threshold for the activation of BCRs resulting from the stimulation by mechanical forces are unknown.
Chen, Haodong, Cao, Yiyun, Wang, Fei, Chen, Xiangjun, Liu, WL (reprint author), Tsinghua Univ, Sch Life Sci, Collaborat Innovat Ctr Diag & Treatment Infect Di, MOE Key Lab Prot Sci, Beijing 100084, Peoples R China., Ji, Qinghua, Lou, Jizhong, Liu, Wanli, Chen, Yingjia, Wan, Zhengpeng, Wang, Jing, Tang, Zhuo   +11 more
core   +1 more source

Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease [PDF]

, 2013
Rho-family GTPases like RhoA and Rac-1 are potent regulators of cellular signaling that control gene expression, migration and inflammation. Activation of Rho-GTPases has been linked to podocyte dysfunction, a feature of chronic kidney diseases (CKD). We
Liliana Schäfer, Christian Fork (70601), Brandes, Ralf P., Brandes, Ralf, Schäfer, Liliana, Pavenstädt, Hermann, Kerstin Amann, Felix Jansen, Kerstin Sander (481042), Jung, Oliver, Ralf P Brandes, Holger Stark, Hermann Pavenstädt, Löhn, Matthias, Oliver Plettenburg (481045), Plettenburg, Oliver, Hartmut Ruetten (481044), Felix Jansen (362745), Holger Stark (4694), Christoph Daniel (282746), Liliana Schäfer (481043), Kerstin Amann (186160), Oliver Jung (362744), Ralf P. Brandes (362753), Kerstin Sander, Oliver Jung, Fork, Christian, Babelova, Andrea, Matthias Löhn, Hermann Pavenstädt (108698), Sander, Kerstin, Ruetten, Hartmut, Oliver Plettenburg, Hartmut Ruetten, Jansen, Felix, Andrea Babelova, Christian Fork, Stark, Holger, Christoph Daniel, Matthias Löhn (171195), Andrea Babelova (362749), Daniel, Christoph, Amann, Kerstin   +42 more
core   +1 more source

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh, Susmita Sarangi, Caileigh Pudela, Catherine M. Broome, Tara K. Suntum   +4 more
wiley   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source