Results 41 to 50 of about 438,222 (313)

Primary cilia disassembly down regulates mechanosensitive hedgehog signalling: a feedback mechanism controlling ADAMTS-5 expression in chondrocytes [PDF]

, 2014
SummaryObjectiveHedgehog signalling is mediated by the primary cilium and promotes cartilage degeneration in osteoarthritis. Primary cilia are influenced by pathological stimuli and cilia length and prevalence are increased in osteoarthritic cartilage ...
Knight, M.M., Chapple, JP, Chapple, J.P., Knight, MM, Thompson, CL, Thompson, C.L.   +5 more
core   +1 more source

On the mechanism of biological activation by tritium [PDF]

Journal of Environmental Radioactivity, 2016
The mechanism of biological activation by beta-emitting radionuclide tritium was studied. Luminous marine bacteria were used as a bioassay to monitor the biological effect of tritium with luminescence intensity as the physiological parameter tested. Two different types of tritium sources were used: HTO molecules distributed regularly in the surrounding
Rozhko, T. V., Badun, G. A., Razzhivina, I. A., Guseynov, O. A., Guseynova, V. E., Kudryasheva, N. S.   +5 more
openaire   +7 more sources

Study on the mechanism of andrographolide activation

Frontiers in Neuroscience, 2022
Andrographolide is a natural antibiotic that has the ability to dispel heat, detoxify, reduce inflammation, and relieve pain. Recent research has shown that it can exert anti-inflammatory effects via multiple pathways and multiple targets (mediated by NF-κB, JAK/STAT, T cell receptor, and other signaling pathways).
Qihan Cai, Weina Zhang, Yanan Sun, Lu Xu, Mengmeng Wang, Xinliang Wang, Siming Wang, Zhiyu Ni, Zhiyu Ni, Zhiyu Ni   +9 more
openaire   +3 more sources

Mechanochemical Treatment for the Extraction of Lithium from Hard Rock Minerals: A Comprehensive Review

Metals
Lithium (Li) extraction from Li hard rock minerals involves thermal activation at elevated temperatures and the use of corrosive reagents. The reagents can damage the environment if they are not adequately contained as part of the process, and the high ...
Yuik Eom, Laurence Dyer, Aleksandar N. Nikoloski, Richard Diaz Alorro   +3 more
doaj   +1 more source

Injurious mechanical ventilation affects neuronal activation in ventilated rats [PDF]

, 2011
Survivors of critical illness often have significant long-term brain dysfunction, and routine clinical procedures like mechanical ventilation (MV) may affect long-term brain outcome. We aimed to investigate the effect of the increase of tidal volume (Vt)
Gemma Fuster, Fuster, Gemma, Villar, Jesús, Jesús Villar, Octavi Martí-Sistac, López-Aguilar, Josefina, Martí-Sistac, Octavi, María Quilez, Lluís Blanch, María Elisa Quilez, Josefina López-Aguilar, Carlos Flores, Flores, Carlos, Blanch, Lluís, Quílez Tierno, María Elisa   +14 more
core   +1 more source

Mechanotransduction in fibroblasts [PDF]

, 2011
Response to mechanical stress is important for tissue homeostasis, tissue architecture and muscle regeneration. All cells of an organism are subject to at least one of three types of mechanical stress: compression, shear stress or tension.
Brosig, Michaela
core   +1 more source

Effect of Curing Temperature, Activator Solution Composition and Particle Size in Brazilian Fly-Ash Based Geopolymer Production [PDF]

Materials Research, 2019
The geopolymer binder is a relatively new class of inorganic binding material of elevated mechanical strength and good chemical properties. This can be produced using clay minerals or byproducts of the industrial processes, such as metakaolin, fly-ash ...
Adriano Galvão Souza Azevedo, Kurt Strecker, Lívia Abreu Barros, Luis Fernando Tonholo, Carolina Torga Lombardi   +4 more
doaj   +1 more source

Tribochemistry, Mechanical Alloying, Mechanochemistry: What is in a Name?

Frontiers in Chemistry, 2021
Over the decades, the application of mechanical force to influence chemical reactions has been called by various names: mechanochemistry, tribochemistry, mechanical alloying, to name but a few.
Adam A. L. Michalchuk, Elena V. Boldyreva, Elena V. Boldyreva, Ana M. Belenguer, Franziska Emmerling, Vladimir V. Boldyrev, Vladimir V. Boldyrev   +6 more
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

On the Mechanism of Ezrin Activation

Biophysical Journal
ABSTRACT Ezrin is a peripheral membrane protein that contributes to the organization and stability of cellular membrane structures by reversibly linking the plasma membrane to actin filaments. The formation of this membrane-actin linkage has been experimentally shown to require ezrin N-terminal (FERM) domain binding ...
Dovydas Vasiliauskas, Jeriann Beiter, Sahithya Sridharan Iyer, Andrew T. Lombardo, Michelle C. Mendoza, Gregory A. Voth   +5 more
openaire   +2 more sources