Results 1 to 10 of about 797,090 (316)

Malignancy-Associated Regions of Transcriptional Activation: Gene Expression Profiling Identifies Common Chromosomal Regions of a Recurrent Transcriptional Activation in Human Prostate, Breast, Ovarian, and Colon Cancers

Neoplasia: An International Journal for Oncology Research, 2003
Despite remarkable advances in our understanding of a genetic basis of cancer, the precise molecular definition of the phenotypically relevant genetic features associated with human epithelial malignancies remains a significant and highly relevant ...
Gennadi V. Glinsky, Anja Krones-Herzig, Anna B. Glinskii   +2 more
doaj   +3 more sources

Transcriptional Activation of Inflammatory Genes: Mechanistic Insight into Selectivity and Diversity

Biomolecules, 2015
Acute inflammation, an integral part of host defence and immunity, is a highly conserved cellular response to pathogens and other harmful stimuli. An inflammatory stimulation triggers transcriptional activation of selective pro-inflammatory genes that ...
Afsar U. Ahmed, Bryan R. G. Williams, Gregory E. Hannigan   +2 more
doaj   +3 more sources

Identification and Analysis of MYB Gene Family for Discovering Potential Regulators Responding to Abiotic Stresses in Curcuma wenyujin

Frontiers in Genetics, 2022
MYB superfamily is one of the most abundant families in plants, and plays critical role in plant growth, development, metabolism regulation, and stress response.
Qiuhui Wei, Qiuhui Wei, Yuyang Liu, Yuyang Liu, Kaer Lan, Kaer Lan, Xin Wei, Xin Wei, Tianyuan Hu, Tianyuan Hu, Rong Chen, Rong Chen, Shujuan Zhao, Shujuan Zhao, Xiaopu Yin, Xiaopu Yin, Tian Xie, Tian Xie   +17 more
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Interferon Regulatory Factors Functioned as Activators of the Interferon Pathway in the Scallop Chlamys farreri

Frontiers in Marine Science, 2022
Interferon regulatory factors (IRFs) are a family of transcription factors that control many facets during innate and adaptive immune responses. Vertebrate IRFs play important roles in regulating the expression of interferons (IFNs) and IFN-stimulated ...
Naina Hu, Shanshan Lian, Shanshan Lian, Xiaomei Zhu, Xiaomei Chen, Fengzhi Sun, Lingling Zhang, Lingling Zhang, Shi Wang, Shi Wang, Shi Wang, Zhenmin Bao, Zhenmin Bao, Zhenmin Bao, Jingjie Hu, Jingjie Hu   +15 more
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RNA as a Transcriptional Activator [PDF]

Chemistry & Biology, 2003
Two recent reports demonstrate that in vivo selection can isolate novel RNAs that activate transcription when tethered to a gene promoter. This highlights the structural plasticity that allows RNA to fulfill many functions normally carried out by proteins.
Gottesfeld, Joel M, Barbas, Carlos F
openaire   +2 more sources

Epiprofin Transcriptional Activation Promotes Ameloblast Induction From Mouse Induced Pluripotent Stem Cells via the BMP-Smad Signaling Axis

Frontiers in Bioengineering and Biotechnology, 2022
The transcriptional regulation of induced pluripotent stem cells (iPSCs) holds promise for their directed differentiation into ameloblasts, which are usually lost after tooth eruption.
Xinchao Miao, Xinchao Miao, Kunimichi Niibe, Yunyu Fu, Maolin Zhang, Maolin Zhang, Praphawi Nattasit, Yumi Ohori-Morita, Takashi Nakamura, Xinquan Jiang, Hiroshi Egusa, Hiroshi Egusa   +11 more
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Generation of functional NaV1.5 current by endogenous transcriptional activation of SCN5A

Biotechnology & Biotechnological Equipment, 2021
The sodium channel NaV1.5, which is encoded by the SCN5A gene, underlies the fast upstroke of cardiac action potential and thus plays a crucial role in cardiac electrophysiology, but the mechanism governing the regulation of NaV1.5 has not been fully ...
Liang Xu, Rui Shi
doaj   +1 more source

Duck Plague Virus pUL48 Protein Activates the Immediate-Early Gene to Initiate the Transcription of the Virus Gene

Frontiers in Microbiology, 2021
Duck plague caused by the duck plague virus (DPV) is an infectious disease that seriously harms the waterfowl breeding industry. The VP16 protein of α herpesvirus can bind to specific cis-acting elements upstream of the promoter of the immediate-early ...
Tong Zhou, Tong Zhou, Tong Zhou, Dengjian Fan, Dengjian Fan, Dengjian Fan, Mingshu Wang, Mingshu Wang, Mingshu Wang, Anchun Cheng, Anchun Cheng, Anchun Cheng, Ying Wu, Ying Wu, Ying Wu, Qiao Yang, Qiao Yang, Qiao Yang, Bin Tian, Bin Tian, Bin Tian, Renyong Jia, Renyong Jia, Renyong Jia, Xumin Ou, Xumin Ou, Xumin Ou, Sai Mao, Sai Mao, Sai Mao, Di Sun, Di Sun, Di Sun, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Dekang Zhu, Dekang Zhu, Shun Chen, Shun Chen, Shun Chen, Mafeng Liu, Mafeng Liu, Mafeng Liu, Xin-Xin Zhao, Xin-Xin Zhao, Xin-Xin Zhao, Juan Huang, Juan Huang, Juan Huang, Qun Gao, Qun Gao, Qun Gao, Yanling Yu, Yanling Yu, Yanling Yu, Ling Zhang, Ling Zhang, Ling Zhang   +58 more
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Transcriptional activators in yeast [PDF]

Nucleic Acids Research, 2006
Eukaryotic transcription activation domains (ADs) are not well defined on the proteome scale. We systematicallly tested approximately 6000 yeast proteins for transcriptional activity using a yeast one-hybrid system and identified 451 transcriptional activators.
Titz, B., Thomas, S., Rajagopala, S. V., Chiba, T., Ito, T., Uetz, P.   +5 more
openaire   +3 more sources

Transcriptome analysis provides StMYBA1 gene that regulates potato anthocyanin biosynthesis by activating structural genes

Frontiers in Plant Science, 2023
Anthocyanin biosynthesis is affected by light, temperature, and other environmental factors. The regulation mode of light on anthocyanin synthesis in apple, pear, tomato and other species has been reported, while not clear in potato.
Xijuan Zhao, Xijuan Zhao, Huiling Zhang, Tengfei Liu, Yanan Zhao, Xinxi Hu, Shengxuan Liu, Yuan Lin, Botao Song, Changzheng He   +9 more
doaj   +1 more source