Results 21 to 30 of about 797,090 (316)

Human papillomavirus 16 L2 inhibits the transcriptional activation function, but not the DNA replication function, of HPV-16 E2 [PDF]

open access: yes, 2005
In this study we analysed the outcome of the interaction between HPV-16 L2 and E2 on the transactivation and DNA replication functions of E2. When E2 was expressed on its own, it transactivated a number of E2-responsive promoters but co-expression of L2 ...
Morgan, I.M.   +11 more
core   +1 more source

Transcriptional regulation of the urokinase receptor (u-PAR) - A central molecule of invasion and metastasis [PDF]

open access: yes, 2003
The phenomenon of tumor-associated proteolysis has been acknowledged as a decisive step in the progression of cancer. This short review focuses on the urokinase receptor (u-PAR), a central molecule involved in tumor-associated invasion and metastasis ...
Fuchs, T., Allgayer, H.
core   +1 more source

Dengue virus infection induces chromatin remodeling at locus AAEL006536 in the midgut of Aedes aegypti

open access: yesSalud Pública de México, 2017
Objective. To identify and characterize Aedes aegypti’s AAEL006536 gene proximal upstream cis-regulatory sequences activated by dengue virus infection. Materials and methods. A. aegypti Rockefeller strain mosquitoes were blood fed or infected with dengue
Graciela Gleason-Rodríguez   +4 more
doaj   +1 more source

The RhoA transcriptional program in pre-T cells [PDF]

open access: yes, 2007
The GTPase RhoA is essential for the development of pre-T cells in the thymus. To investigate the mechanisms used by RhoA to control thymocyte development we have used Affymetrix gene profiling to identify RhoA regulated genes in T cell progenitors.
Lightfoot, K.   +5 more
core   +1 more source

JAK/STAT-deficient cell lines

open access: yesBrazilian Journal of Medical and Biological Research, 1998
Mutant cell lines B3 and B10, which are unresponsive to both interferon (IFN)-alpha and IFN-gamma, and line B9, which does not respond to IFN-gamma stimulation, are described.
C.A. Bonjardim
doaj   +1 more source

Transcriptional activity by cocaine–amphetamine-regulated transcript [PDF]

open access: yesMolecular Psychiatry, 2007
Cocaine–amphetamine-regulated transcript (CART) gene was identified in 1995 in a search for mRNAs in the striatum acutely upregulated by psychostimulants.1 CART is highest expressed in the hypothalamus and widely expressed in the central and peripheral nervous systems, as well as in endocrine cells.1, 2 CART peptides have received much attention as ...
P, Mao, R, Jacks
openaire   +2 more sources

Complex coordination of cell plasticity by a PGC-1α-controlled transcriptional network in skeletal muscle [PDF]

open access: yes, 2015
Skeletal muscle cells exhibit an enormous plastic capacity in order to adapt to external stimuli. Even though our overall understanding of the molecular mechanisms that underlie phenotypic changes in skeletal muscle cells remains poor, several factors ...
Handschin, Christoph   +5 more
core   +1 more source

The peroxisome proliferator-activated receptor γ coactivator 1α/β (PGC-1) coactivators repress the transcriptional activity of NF-κB in skeletal muscle cells [PDF]

open access: yes, 2013
A persistent, low-grade inflammation accompanies many chronic diseases that are promoted by physical inactivity and improved by exercise. The beneficial effects of exercise are mediated in large part by peroxisome proliferator-activated receptor γ ...
Handschin, Christoph   +6 more
core   +1 more source

Isolation and Functional Analysis of the bZIP Transcription Factor Gene TaABP1 from a Chinese Wheat Landrace

open access: yesJournal of Integrative Agriculture, 2012
In plants, basic leucine zipper (bZIP) transcription factors play important roles in regulatory processes, including stress response, pathogenic defense and light response as well as organ and tissue differentiation.
Xin-you CAO   +7 more
doaj   +1 more source

The Conserved Transcriptional Activation Activity Identified in Dual-Specificity Tyrosine-(Y)-Phosphorylation-Regulated Kinase 1

open access: yesBiomolecules, 2023
Dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1 (DYRK1) encodes a conserved protein kinase that is indispensable to neuron development.
Xiuke Ouyang   +4 more
doaj   +1 more source

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