Results 191 to 200 of about 898,493 (283)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

A Lab-Scale Evaluation of Parameters Influencing the Mechanical Activation of Kaolin Using the Design of Experiments. [PDF]

Materials (Basel)
Mañosa J, Alvarez-Coscojuela A, Maldonado-Alameda A, Chimenos JM.   +3 more
europepmc   +1 more source

Modulating the Mechanical Activation of TRPV4 at the Cell-Substrate Interface. [PDF]

Front Bioeng Biotechnol, 2020
Sianati S, Schroeter L, Richardson J, Tay A, Lamandé SR, Poole K.   +5 more
europepmc   +1 more source

Mechanical Activation of MscL Revealed by a Locally Distributed Tension Molecular Dynamics Approach. [PDF]

Biophys J, 2021
Rajeshwar T R, Anishkin A, Sukharev S, Vanegas JM.   +3 more
europepmc   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Mechanical activation and expression of HSP27 in epithelial ovarian cancer. [PDF]

Sci Rep
Buckley M, Kramer M, Johnson B, Huskin G, Berry J, Sewell-Loftin MK.   +5 more
europepmc   +1 more source

Microstructural and Optical Properties of MgAl₂O₄ Spinel: Effects of Mechanical Activation, Y₂O₃ and Graphene Additions. [PDF]

Materials (Basel), 2021
Obradovic N, Fahrenholtz WG, Corlett C, Filipovic S, Nikolic M, Marinkovic BA, Failla S, Sciti D, Di Rosa D, Sani E.   +9 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Modeling mechanical activation of macrophages during pulmonary fibrogenesis for targeted anti-fibrosis therapy. [PDF]

Sci Adv
Xu Y, Ying L, Lang JK, Hinz B, Zhao R.
europepmc   +1 more source