Results 211 to 220 of about 915,324 (354)

Transient mechanical activation of the Piezo1 channel facilitates ex vivo expansion of hematopoietic stem cells. [PDF]

Cell Res
Wang Q, Zeng X, Yang H, Lu H, Jiang L, Xu L, Li J, Li J, Han Y, Wu X, Zhou Y, Chen X, Zhao Y, Shi J, Luo Y, Ni F, Sun J, Zhao Q, Yang F, Xia P, Jiang H, Huang H, Qian P.   +22 more
europepmc   +1 more source

Multistage Mechanical Activation of Multilayer Carbon Nanotubes in Creation of Electric Heaters with Self-Regulating Temperature. [PDF]

Materials (Basel), 2021
Shchegolkov AV, Jang SH, Shchegolkov AV, Rodionov YV, Glivenkova OA.   +4 more
europepmc   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Enhanced Leaching of Lepidolite by Acidophilic Microorganisms Under Mechanical Activation. [PDF]

Microorganisms
Li J, Wang M, Zhang R, Liu H, Huang S, Liu Y, Liao R, Vardanyan A, Xia J, Wang J.   +9 more
europepmc   +1 more source

Targeting the latest site of left ventricular mechanical activation is associated with improved long-term outcomes for recipients of cardiac resynchronization therapy. [PDF]

Heart Rhythm O2, 2022
Borgquist R, Barrington WR, Bakos Z, Werther-Evaldsson A, Saba S.   +4 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Mechanical Activation of cPLA2 Impedes Fatty Acid β-Oxidation in Vein Grafts. [PDF]

Adv Sci (Weinh)
Fan L, Tang Y, Liu J, Liu Y, Xu Y, Liu J, Liu H, Pang W, Guo Y, Yao W, Zhang T, Peng Q, Zhou J.   +12 more
europepmc   +1 more source

KOH-activated fly ash as a binder for chemical stabilization of quarry sludge: mechanical and microstructural validation

Jose Zelaya, Nicolas Pardo, Y.P Arias-Jaramillo   +2 more
openalex   +1 more source

Author response: OSCA/TMEM63 are an evolutionarily conserved family of mechanically activated ion channels

, 2018
Swetha E. Murthy, Adrienne E. Dubin, Tess Whitwam, Sebastian Jojoa-Cruz, Stuart M. Cahalan, Seyed Ali Reza Mousavi, Andrew B. Ward, Ardem Patapoutian   +7 more
openalex   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source