Results 201 to 210 of about 317,079 (268)

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Nondestructive Mechanical Characterization of Bioengineered Tissues by Digital Holography. [PDF]

ACS Biomater Sci Eng
Hiscox C, Li J, Gao Z, Korkin D, Furlong C, Billiar K.   +5 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Preparation and mechanical characterization of pressed carbonized wood sawdust bio-composite. [PDF]

Sci Rep
Rahmani H, Algirdas A, Shestavetska A, Vaiciukyniene D.   +3 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Mechanical Characterization of Porous Bone-like Scaffolds with Complex Microstructures for Bone Regeneration. [PDF]

Bioengineering (Basel)
Coburn B, Salary RR.
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Novel Magnetically Charged Grafts for Vascular Repair: Process Optimization, Mechanical Characterization and In Vitro Validation. [PDF]

Polymers (Basel)
Cruz-Maya I, De Santis R, Lanotte L, Guarino V.   +3 more
europepmc   +1 more source

Physico-mechanical characterization of 3D-printed PLGA for patient-specific resorbable implants in craniofacial surgery. [PDF]

Sci Rep
Kulker D, Pepin J, Rosa B, Laure B, Venin M, Biglione J, Pare A.   +6 more
europepmc   +1 more source

Mechanical Characterization of a Novel Cyclic Olefin-Based Hot-Melt Adhesive. [PDF]

Materials (Basel)
Rodrigues VCMB, Venâncio ATF, Marques EAS, Carbas RJC, Klein A, Kazuhiro E, Nelson B, Silva LFMD.   +7 more
europepmc   +1 more source