Results 41 to 50 of about 115,505 (280)

Ethnic Differences in the Association Between SOD2 rs4880 and Hepatotoxicity in Pediatric Acute Lymphoblastic Leukemia: A Report From the REDIAL Consortium

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason   +14 more
wiley   +1 more source

High-frequency oscillatory ventilation in pediatric acute hypoxemic respiratory failure: disease-specific morbidity survival analysis. [PDF]

open access: yes, 2012
BackgroundMultiple ventilatory strategies for acute hypoxemic respiratory failure (AHRF) in children have been advocated, including high-frequency oscillatory ventilation (HFOV).
Babbitt, Christopher J   +5 more
core   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

Peripartum cardiomyopathy: diagnosis and management [PDF]

open access: yes, 2017
No abstract ...
Coats, Caroline J.   +5 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Accuracy of the HeartMate 3 Left Ventricular Assist Device Flow Estimation

open access: yesScientific Reports
Left ventricular assist devices (LVADs), such as the HeartMate 3 (HM3), are a treatment option for advanced heart failure (HF). Non-invasive monitoring of heart-pump interaction is crucial but relies on estimated parameters only.
Theodor Abart   +6 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Mechanical Circulatory Support [PDF]

open access: yesCirculation, 2007
Mechanical cardiac assistance had its origins as an offshoot from the development of cardiopulmonary bypass. Early efforts in the design and development of devices were focused on providing support for the body and the heart during periods of recovery from impaired cardiac function following unsuccessful cardiac surgery and / or acute myocardial ...
Joe Helou, Robert L. Kormos
openaire   +2 more sources

Impact of adjustable resistance clamps on the in-vitro hemolysis assessment of blood pumps

open access: yesScientific Reports
Adjustable resistance clamps are essential to regulate flow and pressure in in-vitro test loops designed to evaluate hemolysis in blood pumps. However, their contribution to overall hemolysis remains unclear.
Krishnaraj Narayanaswamy   +6 more
doaj   +1 more source

The European Registry for Patients with Mechanical Circulatory Support (EUROMACS): first annual report† [PDF]

open access: yes, 2017
The European Registry for Patients with Mechanical Circulatory Support (EUROMACS) was founded on 10 December 2009 with the initiative of Roland Hetzer (Deutsches Herzzentrum Berlin, Berlin, Germany) and Jan Gummert (Herz- und Diabeteszentrum Nordrhein ...
Bushnaq, Hasan   +14 more
core  

Home - About - Disclaimer - Privacy