Results 51 to 60 of about 441,732 (325)

Complications of Continuous-Flow Mechanical Circulatory Support Devices

Clinical Medicine Insights: Cardiology, 2015
Left ventricular assist devices (LVADs), more importantly the continuous-flow subclass, have revolutionized the medical field by improving New York Heart Association (NYHA) functional class status, quality of life, and survival rates in patients with ...
Harsh Patel, Raef Madanieh, Constantine E. Kosmas, Satya K. Vatti, Timothy J. Vittorio   +4 more
doaj   +2 more sources

Editorial: Mechanical circulatory support therapy for biventricular failure [PDF]

Frontiers in Cardiovascular Medicine
Jamshid H. Karimov, Jamshid H. Karimov, Jamshid H. Karimov, Kiyotaka Fukamachi, Kiyotaka Fukamachi, Kiyotaka Fukamachi, Toru Masuzawa   +6 more
doaj   +2 more sources

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Analysis of squeal noise and mode coupling instabilities including damping and gyroscopic effects [PDF]

European Journal of Mechanics - A/Solids 27, 2 (2008) 141-160, 2008
This paper deals with an audible disturbance known as automotive clutch squeal noise from the viewpoint of friction-induced mode coupling instability. Firstly, an auto-coupling model is presented showing a non-conservative circulatory effect originating from friction forces.
arxiv   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

FEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung, Mikhail G. Dozmorov, SuJeong Song, Theingi Aung, Min Hee Park, Patricia J. Sime, Wook‐Jin Chae   +6 more
wiley   +1 more source

Mechanical Circulatory Support for Complex High-risk Percutaneous Coronary Intervention

US Cardiology Review, 2023
Technological and procedural innovations presently permit the safe and effective performance of increasingly complex percutaneous coronary interventions, while new mechanical circulatory support devices offer circulatory and ventricular support to ...
Alexander G Truesdell, Rhian Davies, Moemen Eltelbany, Michael Megaly, Carolyn Rosner, Lindsey A Cilia   +5 more
doaj   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Association between Public Reporting of Outcomes and the Use of Mechanical Circulatory Support in Patients with Cardiogenic Shock

Journal of Interventional Cardiology, 2019
Risk-averse behavior has been reported among physicians and facilities treating cardiogenic shock in states with public reporting. Our objective was to evaluate if public reporting leads to a lower use of mechanical circulatory support in cardiogenic ...
Vikas Singh, Rodrigo Mendirichaga, Parth Bhatt, Ghanshyambhai Savani, Anil K. Jonnalagadda, Igor Palacios, Mauricio G. Cohen, William W. O’Neill   +7 more
doaj   +1 more source

Thyroid Storm Patients With Elevated Brain Natriuretic Peptide Levels and Associated Left Ventricular Dilatation May Require Percutaneous Mechanical Support

Critical Care Explorations, 2021
OBJECTIVES:. To determine the characteristics of thyroid storm patients with acute decompensated heart failure who should be candidates for temporary percutaneous mechanical circulatory support in addition to beta-blocker treatment to prevent cardiogenic
Marina Arai, MD, Yasuhide Asaumi, MD, PhD, Shunsuke Murata, PhD, Hideo Matama, MD, Satoshi Honda, MD, PhD, Fumiyuki Otsuka, MD, PhD, Yoshio Tahara, MD, PhD, Yu Kataoka, MD, PhD, Kunihiro Nishimura, MD, PhD, Teruo Noguchi, MD, PhD   +9 more
doaj   +1 more source