Results 51 to 60 of about 239,955 (288)

Women in mechanical circulatory support: She persisted!

open access: yesFrontiers in Cardiovascular Medicine, 2022
Many women physicians have blazed trails and played instrumental roles in advancing the field of Advanced Heart Failure (AHF), Mechanical Circulatory Support (MCS), and cardiac transplantation to its current recognition and glory.
Kelley N. Benck   +2 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Early Escalation of Mechanical Circulatory Support Stabilizes and Potentially Rescues Patients in Refractory Cardiogenic Shock

open access: yesCirculation: Heart Failure, 2020
Supplemental Digital Content is available in the text. Background: Limited progress has been made in the management of cardiogenic shock (CS). Morbidity and mortality of refractory CS remain high.
J. Tongers   +10 more
semanticscholar   +1 more source

Platelet Dysfunction During Mechanical Circulatory Support

open access: yesArteriosclerosis, Thrombosis and Vascular Biology, 2021
Supplemental Digital Content is available in the text. Objective: Mechanical circulatory support has emerged as lifesaving therapy for patients with advanced heart failure.
Y. Roka-Moiia   +6 more
semanticscholar   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Temporary Mechanical Circulatory Support: A Review of the Options, Indications, and Outcomes

open access: yesClinical Medicine Insights: Cardiology, 2014
Cardiogenic shock remains a challenging disease entity and is associated with significant morbidity and mortality. Temporary mechanical circulatory support (MCS) can be implemented in an acute setting to stabilize acutely ill patients with cardiomyopathy
Nisha A. Gilotra, Gerin R. Stevens
doaj   +1 more source

Current Landscape of Temporary Percutaneous Mechanical Circulatory Support Technology

open access: yesUS Cardiology Review, 2021
Mechanical circulatory support devices provide hemodynamic support to patients who present with cardiogenic shock. These devices work using different mechanisms to provide univentricular or biventricular support.
Rani Upadhyay   +4 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Role of Mechanical Circulatory Support in Acute MI Management

open access: yesUS Cardiology Review, 2023
Cardiogenic shock complicating acute MI carries high mortality and morbidity in many cases. Mechanical circulatory support devices are often used in these cases, aimed at improving patient-centered outcomes, although there is a lack of large randomized ...
Sundeep Kumar   +2 more
doaj   +1 more source

Bridge to transplantation from mechanical circulatory support: a narrative review

open access: yesJournal of Thoracic Disease, 2021
Objective To highlight recent developments in the utilization of mechanical circulatory support (MCS) devices as bridge-to-transplant strategies and to discuss trends in MCS use following the changes to the United Network for Organ Sharing (UNOS) heart ...
A. Zhou   +6 more
semanticscholar   +1 more source

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