Results 61 to 70 of about 510,045 (326)
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Hemodynamics of Prolonged Percutaneous Mechanical Circulatory Support – When Vasodilatation Sets [PDF]
, 2022 Hemodynamics play an important role in cardiogenic shock assessment for prognosis estimation and for phenotyping cardiogenic shock. This is best done by pulmonary artery catheters.
Thiele, Holger
core +1 more source
Accuracy of the HeartMate 3 Left Ventricular Assist Device Flow Estimation
Scientific ReportsLeft ventricular assist devices (LVADs), such as the HeartMate 3 (HM3), are a treatment option for advanced heart failure (HF). Non-invasive monitoring of heart-pump interaction is crucial but relies on estimated parameters only.
Theodor Abart +6 more
doaj +1 more source
Complications of Continuous-Flow Mechanical Circulatory Support Devices
Clinical Medicine Insights: Cardiology, 2015 Left ventricular assist devices (LVADs), more importantly the continuous-flow subclass, have revolutionized the medical field by improving New York Heart Association (NYHA) functional class status, quality of life, and survival rates in patients with ...
Harsh Patel +4 more
doaj +2 more sources
Frontiers in Nutrition, 2023 IntroductionUnhealthy lifestyle behaviours that may contribute to the development of disorders leading to MI include consuming foods with a high glycaemic load and excessive supply of saturated fats, especially trans fats.
Elżbieta Szczepańska +4 more
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Analysis of squeal noise and mode coupling instabilities including damping and gyroscopic effects [PDF]
European Journal of Mechanics - A/Solids 27, 2 (2008) 141-160, 2008 This paper deals with an audible disturbance known as automotive clutch squeal noise from the viewpoint of friction-induced mode coupling instability. Firstly, an auto-coupling model is presented showing a non-conservative circulatory effect originating from friction forces.
arxiv +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Mechanical Circulatory Support in COVID-19
Heart Failure Clinics, 2022 Despite aggressive care, patients with cardiopulmonary failure and COVID-19 experience unacceptably high mortality rates. The use of mechanical circulatory support devices in this population offers potential benefits but confers significant morbidity and novel challenges for the clinician.
Gorder, Kari +6 more
openaire +3 more sources
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source