Results 101 to 110 of about 27,037,911 (301)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Kinematics and Transmission Performance Analyses of a 2T2R Type 4-DOF Spatial Parallel Manipulator

open access: yesJournal of Robotics, 2018
A 2-RPU&2-SPS spatial parallel mechanism (SPM) is researched. Firstly, the number and property of degrees of freedom (DOF) of the SPM are analyzed by screw theory.
Haiyan An   +3 more
doaj   +1 more source

Discontinuous integral control for mechanical systems [PDF]

open access: yes2016 14th International Workshop on Variable Structure Systems (VSS), 2016
For mechanical systems we present a controller able to track an unknown smooth signal, converging in finite time and by means of a continuous control signal. The control scheme is insensitive against unknown perturbations with bounded derivative. The controller consists of a non locally Lipschitz state feedback control law, and a discontinuous integral
openaire   +3 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Measurement of concentration distribution in endothelial surface layer using super resolution LIF technique

open access: yesNihon Kikai Gakkai ronbunshu, 2015
In order to investigate an effect of glycocalyx layer covering vascular endothelial cell surface on molecular transport, a super resolution LIF (Laser Induced Fluorescence) technique for concentration distributions measurement with high spatial ...
Katsuo MOGI   +3 more
doaj   +1 more source

Simple mechanical control systems with constraints [PDF]

open access: yesIEEE Transactions on Automatic Control, 2000
Summary: We apply some recently developed control theoretic techniques to the analysis of a class of mechanical systems with constraints. Certain simple aspects of the theory of affine connections play an important part in our presentation. The necessary background is presented in order to illustrate how the methods may be applied.
openaire   +2 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Supervisory control of multilevel discrete-event systems with a bus structure

open access: yes, 2019
High-tech systems often contain a few components with many dependencies across the system, acting as system-level integrating components. In a hierarchical system decomposition, such so-called bus components tend to be placed in the top node.
van de Mortel - Fronczak, Asia   +7 more
core   +1 more source

Deep Learning-Based Classification of Weld Surface Defects

open access: yesApplied Sciences, 2019
In order to realize the non-destructive intelligent identification of weld surface defects, an intelligent recognition method based on deep learning is proposed, which is mainly formed by convolutional neural network (CNN) and forest random.
Haixing Zhu, Weimin Ge, Zhenzhong Liu
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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