Results 121 to 130 of about 27,037,911 (301)

Global sliding-mode control with generalized sliding dynamics

open access: yes, 2011
[[abstract]]A global sliding-mode control (GSMC) scheme is proposed to provide a framework for ensuring the existence of a sliding mode throughout an entire response.
Chiu, Chien-Wei, Lu, Yu-Sheng
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Control of mechanical systems with constraints: two pendulums case study

open access: yes, 2008
A method for control of mechanical systems under phase constraints, applicable to energy control of Hamiltonian systems is proposed. The constrained energy control problem for two pendulums by a single control action is studied both analytically and ...
Anayevskiy, M.S.   +3 more
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Research on Position-Feedback Control Strategy of Engineered Drilling Rig Hydro-Mechanical Composite Propulsion System

open access: yes
To solve the problem of traditional engineering drilling rig propulsion systems being difficult to adapt to complex working conditions due to their bulky structure and poor load adaptability, this study proposes a new type of mechanical hydraulic ...
Yuanzhou Li   +4 more
core   +1 more source

Recent Advances in Cooling Technology for the Leading Edge of Gas Turbine Blades

open access: yesEnergies
As the inlet temperature of the gas turbine exceeds the high temperature limit of the blade materials, efficient leading edge cooling technologies are crucial for the further development of gas turbines.
Shixing Zhu   +3 more
doaj   +1 more source

System for controlled mechanical therapies of the brain

open access: yesUltrasonics
Transcranial focused ultrasound enables remote targeted therapies that were previously only possible using surgical approaches. Mechanical therapies are particularly attractive due to their confined action and the elimination of the potentially harmful tissue and skull heating. However, systems for controlled mechanical therapies of the brain have been
Eli Finlinson   +3 more
openaire   +2 more sources

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Control of Man-Machine System Based on Virtual Tool Dynamics.

open access: yes, 1994
In this paper, we propose an altrenative control algorithm for the man-macine system. The man-machine system consists of a mechanical system and a human to operate the system.
Yoshio Fujisawa   +5 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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