Results 121 to 130 of about 27,037,911 (301)
Global sliding-mode control with generalized sliding dynamics
[[abstract]]A global sliding-mode control (GSMC) scheme is proposed to provide a framework for ensuring the existence of a sliding mode throughout an entire response.
Chiu, Chien-Wei, Lu, Yu-Sheng
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Control of mechanical systems with constraints: two pendulums case study
A method for control of mechanical systems under phase constraints, applicable to energy control of Hamiltonian systems is proposed. The constrained energy control problem for two pendulums by a single control action is studied both analytically and ...
Anayevskiy, M.S. +3 more
core
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
To solve the problem of traditional engineering drilling rig propulsion systems being difficult to adapt to complex working conditions due to their bulky structure and poor load adaptability, this study proposes a new type of mechanical hydraulic ...
Yuanzhou Li +4 more
core +1 more source
Recent Advances in Cooling Technology for the Leading Edge of Gas Turbine Blades
As the inlet temperature of the gas turbine exceeds the high temperature limit of the blade materials, efficient leading edge cooling technologies are crucial for the further development of gas turbines.
Shixing Zhu +3 more
doaj +1 more source
System for controlled mechanical therapies of the brain
Transcranial focused ultrasound enables remote targeted therapies that were previously only possible using surgical approaches. Mechanical therapies are particularly attractive due to their confined action and the elimination of the potentially harmful tissue and skull heating. However, systems for controlled mechanical therapies of the brain have been
Eli Finlinson +3 more
openaire +2 more sources
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Control of Man-Machine System Based on Virtual Tool Dynamics.
In this paper, we propose an altrenative control algorithm for the man-macine system. The man-machine system consists of a mechanical system and a human to operate the system.
Yoshio Fujisawa +5 more
core +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source

