Results 131 to 140 of about 795,237 (312)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Versatile Control System for Automated Single-Molecule Optical Tweezers Investigations [PDF]

, 2010
We present a versatile control system to automate single-molecule biophysics experiments. This method combines low-level controls into various functional, user-configurable modules, which can be scripted in a domain-specific instruction language.
Steven J. Koch, Richard C. Yeh
core   +1 more source

Thermodynamic and Economic Analyses of a Novel Cooling, Heating and Power Tri-Generation System with Carbon Capture

Atmosphere
The combined cooling, heating, and power (CCHP) system has attracted increasing attention due to its potential outstanding performance in thermodynamics, economics, and the environment. However, the conventional CCHP systems are carbon-intensive.
Linbo Yan, Ziyue Jia, Yang Liu, Cong Geng, Boshu He   +4 more
doaj   +1 more source

Concept Design and Analysis of a Novel Steamer-Filling Robot

Journal of Robotics, 2017
Steamer-filling operation is a crucially important process in the liquor-making process, directly related to liquor yield and liquor quality. But so far, this process is still dominated by manual operation.
Enhong Xing, Bin Li, Xinhua Zhao
doaj   +1 more source

Control system design of mechanical systems with time varying mechanical and control parameters

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2014
A new control framework of motion and/or vibration control system design for mechanical systems with a time varying mechanical and control parameters is studied. As examples of such time varying mechanical and control parameters, we can assume a variable damping or stiffness parameter of semi-active control devices and a time varying weighting function
openaire   +3 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

A data-driven model predictive control approach toward feedback linearization of nonlinear mechanical systems [PDF]

, 2020
This paper presents a novel approach to linearize the input-output (IO) response of nonlinear mechanical systems by using model predictive control (MPC) with integral action and solving a one-step-ahead reference tracking problem.
Vandemaele, S., Oomen, Tom A.E., Desmet, W., Pluymers, B., Floren, Merijn, Noël, Jean-Philippe, Moens, D.   +6 more
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source