Results 151 to 160 of about 795,237 (312)

Damage Tolerant Active Contro l: Concept and State of the Art [PDF]

open access: yes, 2012
Damage tolerant active control is a new research area relating to fault tolerant control design applied to mechanical structures. It encompasses several techniques already used to design controllers and to detect and to diagnose faults, as well to ...
NOBREGA, Euripedes, MECHBAL, Nazih
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Modelling and control of adaptive mechanical structures Proceedings [PDF]

open access: yes, 1998
Adaptive structures (smart structures) are autonomous structural systems with integrated multifunctional smart materials as actuators and sensors, connected by a control system, to facilitate adaptation to changing environmental conditions (e.g.
Gabbert, U. (comp.)   +1 more
core  

Adaptive Control for Nonlinear Mechanical Systems

open access: yesTransactions of the Society of Instrument and Control Engineers, 1986
In this paper, we show a design method of model reference adaptive control system for nonlinear mechanical systems using the special features of the mechanical system, without using any linearizations or approximations. The proposed MRACS assures the global asymptotic stability and the boundedness of internal signals of the whole system.
openaire   +2 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Modelling and Control for Soft Finger Manipulation and Human-Robot Interaction [PDF]

open access: yes, 2010
One of the greatest challenges of humanoid robotics is to provide a robotic systems with autonomous and dextrous skills. Dextrous manipulation skills, for personal and service robots in unstructured environments, are of fundamental importance, in order ...
Ficuciello, Fanny
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Education system workforce development [PDF]

open access: yes, 2019
Thesis: S.M., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2019Cataloged from PDF version of thesis.Includes bibliographical references (pages 47-51).The shortage of skilled workers who can use robots and advanced ...
Ng, Jerry,(Mechanical engineering scientist)Massachusetts Institute o Technology.
core  

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