Results 141 to 150 of about 2,379,090 (281)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Mechanical Engineering Graduate Program Handbook, 2023-2024 [PDF]

, 2023
Mechanical Engineering
core  

Impact of dead zones on the response of a hadron calorimeter with projective and non-projective geometry

, 2011
The aim of this study is to find an optimal mechanical design of the hadronic calorimeter for SiD detector which takes into account engineering as well as physics requirements. The study focuses on the crack effects between two modules for various barrel
Blaha, J., Geffroy, N., Karyotakis, Y.
core   +1 more source

Development of improved ATF engineering alloy - Mechanical testing of Phase 2 alloy

, 2015
O. Anderoglu, Manuel L. Lovato, S.A. Maloy   +2 more
openalex   +2 more sources

Directions in mechanical engineering

Journal of King Saud University: Engineering Sciences, 2014
Richard M. Lueptow
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Mechanical Engineering Design Project report: Enabler control systems [PDF]

The Controls Group was assigned the responsibility for designing the Enabler's control system. The requirement for the design was that the control system must provide a simple user interface to control the boom articulation joints, chassis articulation ...
Cullen, Christian, Delvecchio, Dave, Havics, Andrew A., Scarborough, Alan   +3 more
core   +1 more source

Strain/stress engineering on the mechanical and electronic properties of phosphorene nanosheets and nanotubes

, 2017
Wei Zhang, Jiuren Yin, Ping Zhang, Yanhuai Ding   +3 more
openalex   +2 more sources

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source

Application of Peter Chew Rule To Jib Crane (Mechanical Engineering)

, 2023
Chew P.
europepmc   +1 more source