Results 151 to 160 of about 2,446,527 (268)

Assessment model for multivariable fatigue performance of EA4T axles containing defects : ^a School of mechanical Engineering, Chengdu University, Chengdu 610,106, China. [PDF]

Sci Rep
Luo Y, Li G, Qi C, Li C, Hu Y.
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Bio-inspired designs: leveraging biological brilliance in mechanical engineering-an overview. [PDF]

3 Biotech
Fattepur G, Patil AY, Kumar P, Kumar A, Hegde C, Siddhalingeshwar IG, Kumar R, Khan TMY.   +7 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Faculty of Mechanical Engineering: Past and Present [PDF]

, 2013
Babayan, Vyacheslav, Olishevska, V. E., Shvets, O. D.   +2 more
core  

Research on the maker learning experiences of engineering college students majoring in mechanical engineering in China. [PDF]

Sci Rep
Yang W, Chen P.
europepmc   +1 more source

Application of Peter Chew Method in Mechanical Engineering (Jib Crane)

, 2023
Chew P.
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

The role of generative AI tools in shaping mechanical engineering education from an undergraduate perspective. [PDF]

Sci Rep
Akolekar H, Jhamnani P, Kumar V, Tailor V, Pote A, Meena A, Kumar K, Challa JS, Kumar D.   +8 more
europepmc   +1 more source

Exploring bias in mechanical engineering students' perceptions of classmates. [PDF]

PLoS One, 2019
Salehi S, Holmes NG, Wieman C.
europepmc   +1 more source