Results 51 to 60 of about 2,411,563 (322)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
A phenomenal basis for hybrid modelling [PDF]
, 2017 This work in progress extends the new mechanical philosophy from science to engineering. Engineering is the practice of organising the design and construction of artifices that satisfy needs in real-world contexts.
Hall, Jon G +2 more
core +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Summary of Research 2000, Department of Mechanical Engineering [PDF]
, 2000 The views expressed in this report are those of the authors and do not reflect the official policy or position of the Department of Defense or U.S.
Faculty of the Naval Postgraduate School, Department of Mechanical Engineering
core
Heat-resistant concrete based on alumina cement from substandard raw material [PDF]
, 2011 Results are provided for development of refractory concrete based on modified alumina cement using chemical industry waste. A quantitative ratio for mixed filler fractions, the effect of production factors on concrete strength, the dependence of its ...
de Arnaldo Araujo, A. +3 more
core +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Machine Design Experiments Using Gears to Foster Discovery Learning [PDF]
, 2015 Machine Design Experiments Using Gears to Foster Discovery Learning For the typical undergraduate engineering student the topic of gears is introduced and discussed in several courses.
Nagurka, Mark L. +1 more
core +1 more source
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Preliminary Concept of an Unmanned Aerial Vehicle for Patrolling of Water Basins [PDF]
Problemy Mechatroniki, 2019 The paper presents a preliminary concept of an unmanned aerial vehicle (UAV) designed with a form of the Kasper wing (known in Polish as the ‘Kasprzyk wing’) and intended for aerial patrolling and monitoring of large water basins, mass gatherings, ground
Edyta ŁADYŻYŃSKA-KOZDRAŚ +3 more
doaj +1 more source