Results 61 to 70 of about 2,474,940 (289)

Polymer reinforcement with nanoparticles [PDF]

open access: yes, 2008
The Polymers and Composites research group belongs to the Materials Science and Engineering and Chemical Engineering Department of the University Carlos III of Madrid, Spain.
Baselga Llidó, Juan
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

DEVELOPING AUTHENTIC ASSESSMENT FOR MECHANICAL ENGINEERING SUBJECT OF VOCATIONAL SCHOOL STUDENTS (ESP) AT SMK N 2 OF BENGKULU

open access: yesJournal of Applied Linguistics and Literature, 2019
This research was aimed to know the appropriate assessment, find out speaking’s authentic assessment material and find out the characteristics of authentic speaking assessment model for Mechanical Engineering of Vocational School.
Erlian Dwisnu
doaj   +5 more sources

Non-holonomy, critical manifolds and stability in constrained Hamiltonian systems

open access: yes, 1999
We approach the analysis of dynamical and geometrical properties of nonholonomic mechanical systems from the discussion of a more general class of auxiliary constrained Hamiltonian systems.
Chen, Thomas
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A new modelling method for satellite solar panel and its correlation verification

open access: yesThe Journal of Engineering
In satellite design and manufacturing, due to the influence of material properties, sandwich structure and equivalent algorithm, there is usually a significant deviation between the theoretical model and the actual physical prototype. To solve the issue,
Shuo Wang   +3 more
doaj   +1 more source

Mechanical Engineering: Medium-Sized Companies with Highest Savings Potential [PDF]

open access: yes
The German mechanical engineering industry, dominated by medium-sized companies, is greatly successful - both on the domestic and on the international market.
Alexander S. Kritikos   +1 more
core  

The Effects of a First Year Engineering Class Using the SCALE-Up Method on Student Retention and Subsequent Student Pass Rates [PDF]

open access: yes, 2019
Due to the increased demand for engineers, the University of Texas at Arlington (UTA) created a new, first year engineering class using the Student-Centered Active Learning Environment with Upside-down Pedagogies (SCALE-Up) method to specifically address
Ewing, David
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy