Results 51 to 60 of about 1,128,815 (309)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
High-temperature quality of accelerated spheroidization on SUP9 leaf spring to enhance machinability
Heliyon, 2018 The high temperature on the austenitization showed the varied results in the fast spheroidization in high carbon leaf spring steel SUP9/55CrMnA. The heating temperature was held for 15 minutes in the austenitization temperature at 800, 850, and 900 °C ...
Hendri Chandra +2 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Revisiting classical design in engineering from a perspective of frugality
Heliyon, 2017 The conservative nature of design in engineering has typically unleashed products fabricated with generous amounts of raw materials. This is epitomized by the factor of safety whose values higher than unity suggests various uncertainties of design that ...
Balkrishna C. Rao
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Lubricant flow analysis for effective lubrication of tractor forward/reverse clutch
Heliyon, 2017 Owing to the high power requirements of tractors, their low-power transmission gears often experience durability problems such as burning of the clutch.
Daekyung Noh +3 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Summary of Research 2001, Department of Mechanical Engineering [PDF]
, 2001 The view expressed in this report are those of the authors and do not reflect the official policy or position of the Department of Defense or U.S. Government.This report contains project summaries ofthe research projects in the Department ofMechanical ...
Faculty of the Department of Mechanical Engineering, Naval Postgraduate School
core
Risks related to the lack of lubrication on surface integrity in drilling
Heliyon, 2019 Drilling processes can significantly affect the surface integrity of metallic components. Thus, the control of the drilling process is of great interest for industry to ensure a satisfactory surface behavior.
Mathieu Girinon +7 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source