Results 71 to 80 of about 7,260,892 (293)

Experimental investigation on mechanical behavior of sandwich structures using Digital Image Correlation (DIC)

open access: yesFracture and Structural Integrity
The aim of this work is to investigate the mechanical behavior of sandwich structures when subjected to edgewise and flatwise compression loadings, using 2D Digital Image Correlation (DIC).
Amina Masmoudi   +5 more
doaj   +1 more source

Understanding the wire electrical discharge machining of Ti6Al4V alloy

open access: yesHeliyon, 2019
Non-conventional machining process for instance, wire electrical discharge machining (WEDM) of titanium alloys is gaining attention due to non-contact nature of this process.
A. Pramanik, A.K. Basak, C. Prakash
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Mechanical dissection in an introductory engineering design module [PDF]

open access: yes, 2010
The introductory design module for first year students in the Department of Mechanical Engineering at the University of Strathclyde uses mechanical dissection as a focus for learning activities that seek to integrate engineering science with the prior ...
McLaren, A.J., Jenkins, Peter
core   +3 more sources

A novel type of semi-active jet turbulence grid

open access: yesHeliyon, 2018
This article describes a novel approach to generate increased turbulence levels in an incoming flow. It relies on a cost-effective and robust semi-active jet grid, equipped with flexible tubes as moving elements attached onto tube connections placed at ...
N. Szaszák   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Numerical investigation of vortex shedding mechanism for staggered rows of cylinders

open access: yesHeliyon, 2019
This numerical investigation deals with study of flow past seven square cylinders arranged in staggered configuration. Simulations to the underlying problem are carried out by using the single relaxation time lattice Boltzmann method.
Ghazala Nazeer   +2 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

The Hypothetic Model of Integrated Production-Based Learning with the 21st Century Learning Skills in Mechanical Engineering

open access: yesJurnal Pendidikan Teknologi dan Kejuruan, 2019
Vocational education building and development must consider the needs of the industry and the demands of 21st-century skills graduates. For these two requirements, it is necessary to innovate the learning model to improve the students’ learning ...
Heri Yudiono   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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