Results 31 to 40 of about 368,575 (291)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Conjugate Heat Transfer Investigation on Swirl-Film Cooling at the Leading Edge of a Gas Turbine Vane

open access: yesEntropy, 2019
Numerical calculation of conjugate heat transfer was carried out to study the effect of combined film and swirl cooling at the leading edge of a gas turbine vane with a cooling chamber inside.
Haifen Du   +4 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Subventionen im Maschinenbau [PDF]

open access: yes, 1999
Das DIW hat im Auftrag der Stiftung IMPULS ein Gutachten erarbeitet, in dem der Frage nachgegangen wurde, in welchem Umfang den Sektoren Maschinenbau und Büromaschinen, ADV Subventionen in Form von Finanzhilfen und Steuervergünstigungen zufließen.
Stille, Frank, Teichmann, Dieter
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Identification Methods and Test Results for Tilting Pad and Fixed Geometry Journal Bearing Dynamic Coefficients – A Review

open access: yesShock and Vibration, 2009
Fluid film journal bearings (FFBs) are used to support high-speed rotors in turbomachinery which often operate above the rotor first bending critical speed.
T.W. Dimond   +3 more
doaj   +1 more source

Monitoring the Joint Area of Composite Membrane Materials

open access: yesApplied Sciences, 2019
Textile membranes are suitable for a wide range of applications due to their user-adjustable properties, which can be modified based on both the textile reinforcement structure and the coating material. Complex dynamic loads are involved in typical usage
Hans Winger   +5 more
doaj   +1 more source

A class of spatial econometric methods in the empirical analysis of clusters of firms in the space [PDF]

open access: yes, 2007
In this paper we aim at identifying stylized facts in order to suggest adequate models of spatial co–agglomeration of industries. We describe a class of spatial statistical methods to be used in the empirical analysis of spatial clusters.
Arbia, Giuseppe   +2 more
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

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